Overview
- Highlights the importance of UPR signaling in regulating endoplasmic reticulum function
- Examines how imbalances in UPR signaling can influence human disease pathogenesis
- Discusses therapeutic potential for UPR-dependent remodeling of ER proteostasis to intervene in etiologically diverse human diseases
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 414)
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Table of contents (8 chapters)
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Front Matter
Keywords
About this book
This volume reviews the current research focused on the functional importance of unfolded protein response (UPR) signaling in the context of health and disease. The chapters present cutting-edge work describing the diverse functions of UPR signaling critical for regulating cellular and organismal physiology under physiologic and pathologic conditions. Written by internationally respected scientists, this volume is designed to provide a broad view of the diverse functional importance of UPR, and as such appeals to clinicians and academic researchers alike.
Editors and Affiliations
About the editors
R. Luke Wiseman
Associate Professor
Department of Molecular Medicine
The Scripps Research Institute MEM 220
La Jolla, CA 92037, USA
Phone: (858) 784-8820
Email: wiseman@scripps.edu
Cole M. Haynes
Associate Professor
University of Massachusetts Medical School
Worcester, MA 01605, USA
Email:Cole.Haynes@umassmed.edu
Bibliographic Information
Book Title: Coordinating Organismal Physiology Through the Unfolded Protein Response
Editors: R. Luke Wiseman, Cole M. Haynes
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-319-78530-1
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG, part of Springer Nature 2018
Hardcover ISBN: 978-3-319-78529-5Published: 27 April 2018
Softcover ISBN: 978-3-030-08723-4Published: 14 December 2018
eBook ISBN: 978-3-319-78530-1Published: 18 April 2018
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: VII, 213
Topics: Immunology, Human Physiology, Neurosciences, Cancer Research, Infectious Diseases