Overview
- Outlines recombinant glycoprotein expression in different host systems
- Discusses the role of glycosylation on protein function and vaccine development
- Updates on cutting edge glycoanalytical technologies
- Sets out future directions in glycobiotechnology and glycoanalysis
Part of the book series: Advances in Biochemical Engineering/Biotechnology (ABE, volume 175)
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Table of contents (17 chapters)
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Front Matter
Keywords
About this book
This book reviews the latest trends in glycobiotechnology, it offers an authoritative discussion about future directions of glycoengineering, and it provides a comprehensive overview about the current and emerging approaches to identify, quantify and characterize glycosylated proteins.
Divided into 14 chapters, the book outlines recombinant glycoprotein expression in mammalian cells, insect cells, yeast, and bacterial systems. It covers the chemical and enzymatic syntheses of glycans and glyconjugates, and addresses the impact of glycosylation on protein function for the development of biologicals including vaccines. In the final chapters of the book, readers will discover more about the state-of-the-art in glycomics, glycoproteomics and glycan array technologies.
Editors and Affiliations
About the editors
Professor Udo Reichl is a Scientific Member of the Max Planck Society, Director of the Bioprocess Engineering Department of the Max Planck Institute for Dynamics of Complex Technical Systems in Magdeburg and Chair of Bioprocess Engineering at the Otto-von-Guericke University Magdeburg. He has profound expertise in the development and optimization of cell culture-based viral vaccine production. His group developed sophisticated analytical tools to monitor process dynamics, metabolism of cell lines, infection dynamics and the glycosylation of viral and recombinant proteins. His list of publications comprises more than 250 peer-reviewed papers and book chapters, and he has filed various patents.
Bibliographic Information
Book Title: Advances in Glycobiotechnology
Editors: Erdmann Rapp, Udo Reichl
Series Title: Advances in Biochemical Engineering/Biotechnology
DOI: https://doi.org/10.1007/978-3-030-69590-3
Publisher: Springer Cham
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer Nature Switzerland AG 2021
Hardcover ISBN: 978-3-030-69589-7Published: 03 July 2021
Softcover ISBN: 978-3-030-69592-7Published: 03 July 2022
eBook ISBN: 978-3-030-69590-3Published: 27 July 2021
Series ISSN: 0724-6145
Series E-ISSN: 1616-8542
Edition Number: 1
Number of Pages: VIII, 463
Number of Illustrations: 300 b/w illustrations, 83 illustrations in colour
Topics: Protein Science, Biotechnology, Industrial Chemistry/Chemical Engineering, Biochemical Engineering