Overview
First textbook to cover cell-specific signaling of over 20 cell-types by experts in the field
Covers topics from ligand/receptor interaction to organ/organism response
Tabular and well-illustrated, will be extremely valuable in the understanding of this complex field
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Table of contents (16 chapters)
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Front Matter
Keywords
About this book
Signal transduction comprises the intracellular biochemical signals which induce the appropriate cell response to an external stimulus. The players in signal transduction are diverse, from small molecules as first messengers, to proteins, receptors, transcription factors, among many others. The different signaling pathways and the crosstalk between them originates the unique signaling profile of every cell type in the human body. The cell signaling specificity depends on several aspects including protein composition, subcellular localization and complexes and gene promoters.
This textbook provides a comprehensive overview of the specific signaling pathways on a variety of human tissues. This information can be of great value for health science researchers, professionals and students to understand key pathways for tissue-specific functions in the plethora of signals, signals receptors, transducers and effectors.
Chapter 3 and 15 are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.Editors and Affiliations
About the editors
Joana Vieira Silva; Laboratory of Signal Transduction, Department of Medical Sciences, Institute of Biomedicine – iBiMED, University of Aveiro, Portugal; Institute for Innovation and Health Research (i3S), University of Porto, Portugal; Department of Microscopy, Laboratory of Cell Biology, and Unit for Multidisciplinary Research in Biomedicine (UMIB), Institute of Biomedical Sciences Abel Salazar (ICBAS), University of Porto, Portugal; joanavieirasilva@ua.pt
Maria João Freitas; Laboratory of Protein Phosphorylation and Proteomics, Department of Cellular and Molecular Medicine, Faculty of Medicine, KU Leuven, Leuven, Belgium; mariajoao.freitas@kuleuven.be
Margarida Fardilha; Laboratory of Signal Transduction, Institute for research in Biomedicine- iBiMED, Medical Sciences Department, University of Aveiro, Aveiro, Portugal; mfardilha@ua.pt
Bibliographic Information
Book Title: Tissue-Specific Cell Signaling
Editors: Joana Vieira Silva, Maria João Freitas, Margarida Fardilha
DOI: https://doi.org/10.1007/978-3-030-44436-5
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-44435-8Published: 30 May 2020
eBook ISBN: 978-3-030-44436-5Published: 29 May 2020
Edition Number: 1
Number of Pages: XVIII, 436
Number of Illustrations: 1 b/w illustrations, 50 illustrations in colour
Topics: Human Genetics, Human Physiology, Cell Biology, Cell Physiology, Molecular Medicine