Overview
- Summarizes the recent advances in potential cancer diagnostic markers in gastrointestinal cancers
- Examines the molecular markers, metabolic markers, circulatory biomarkers, and genetic susceptibility markers in GI cancers
- Discusses the role of GWAS, big data analytics, computation biology, and systems biology in identifying novel biomarkers
- Reviews the use of nanosensors, and electrochemical, optical and DNA biosensors for analyzing markers of GI cancer
Part of the book series: Diagnostics and Therapeutic Advances in GI Malignancies (DTAGIM)
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Table of contents (13 chapters)
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Front Matter
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Emerging Biomarkers for Gastrointestinal Cancer
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Front Matter
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Advances in Biosensors and Detection Technologies for Gastrointestinal Cancer
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Front Matter
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Computational Methods for Identification Gastrointestinal Cancer Biomarkers and Early Diagnosis of GI Cancer
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Front Matter
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Keywords
About this book
This book describes various novel biomarkers for the early diagnosis of gastrointestinal (GI) cancers. It also highlights recent advances in understanding the role of molecular markers and biomarkers, such as volatile biomarkers, serum biomarkers, predictive and prognostic molecular markers for the early detection of GI cancers. Further, it discusses novel biomarkers, including circulating microRNAs, serum microRNA and plasma microRNA in GI cancer.
The book presents breakthrough technologies like ultra-sensitive nano-chips, nanosensors, nanodevices, biosensors, electrochemical biosensors, optical biosensors, DNA biosensors, synthetic biology devices, and 'omics' technologies for the early diagnosis of gastrointestinal cancer. In addition it examines the potential of genome-wide association studies, big data analytics, computation biology, systems biology, and nanotechnology for early diagnostics and therapeutics for gastrointestinal cancer, with a focus on personalized cancertreatment. The book is a valuable source for researchers and clinicians engaged in detection and diagnosis of gastrointestinal cancers.Editors and Affiliations
About the editors
Dr. Neelapu Nageswara Rao Reddy is currently an Assistant Professor at the Department of Biochemistry and Bioinformatics, Institute of Science, Gandhi Institute of Technology and Management (GITAM) (deemed university), India. He obtained his Master’s in Life Science from Pondicherry Central University, and Ph.D. in Evolutionary Bioinformatics from Andhra University, Visakhapatnam, India. His research interests include bioinformatics, cancer, and fungal biology with specialization in drug target discovery, HLA-based peptide vaccine design, genome analysis, phylogenyand evolution. Furthermore, he has expanded his research fields to understanding biochemical mechanisms of stress-induced proteins, structure-function relationship of proteins, and exploring next generation sequencing data to understand traits. He has been a recipient of several fellowships, like CSIR-UGC Junior Research Fellowship; and DAAD Visiting Fellowship, Germany. He has published more than 50 research articles in prestigious peer-reviewed international journals and presented 18 abstracts at various national and international conferences. He has served on the editorial board for a number of national and international journals, and is a member of several international scientific societies and organizations, most importantly, Indian Science Congress & Society of Biological Chemists, India.
Bibliographic Information
Book Title: Recent Advancements in Biomarkers and Early Detection of Gastrointestinal Cancers
Editors: Pallaval Veera Bramhachari, Nageswara Rao Reddy Neelapu
Series Title: Diagnostics and Therapeutic Advances in GI Malignancies
DOI: https://doi.org/10.1007/978-981-15-4431-6
Publisher: Springer Singapore
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Singapore Pte Ltd. 2020
Hardcover ISBN: 978-981-15-4430-9Published: 22 July 2020
Softcover ISBN: 978-981-15-4433-0Published: 23 July 2021
eBook ISBN: 978-981-15-4431-6Published: 21 July 2020
Series ISSN: 2662-2688
Series E-ISSN: 2662-2696
Edition Number: 1
Number of Pages: XXIII, 231
Number of Illustrations: 4 b/w illustrations, 34 illustrations in colour
Topics: Cancer Research, Gene Expression, Gastroenterology, Oncology, Nanotechnology