Overview
- Editors:
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Manfred R. Koller
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Oncosis, San Diego, USA
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Bernhard O. Palsson
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Department of Bioengineering, University of California, San Diego, USA
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John R.W. Masters
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University College London, London, UK
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Table of contents (11 chapters)
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- Ross Tubo, Liesbeth Brown
Pages 1-16
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- Louis C Almekinders, Albert J Banes
Pages 17-25
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- Thomas Oates Jr, Anh M Hoang
Pages 27-41
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- Diane Proudfoot, Catherine M Shanahan
Pages 43-64
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- Louise J Hutley, Felicity S Newell, Steven J Suchting, Johannes B Prins
Pages 173-187
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- Mark F Pittenger, Gabriel Mbalaviele, Marcia Black, Joseph D Mosca, Daniel R Marshak
Pages 189-207
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- Jason Chesney, Richard Bucala
Pages 209-219
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- Lucy Di-Silvio, Neelam Gurav
Pages 221-241
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Back Matter
Pages 242-244
About this book
The human body contains many specialized tissues that are capable of fulfilling an incredible variety of functions necessary for our survival. This volume in the Human Cell Culture Series focuses on mesenchymal tissues and cells. The in vitro study of mesenchymal cells is perhaps the oldest form of human cell culture, beginning with the culturing of fibroblasts. Fibroblasts have long been generically described in the literature, arising from many tissue types upon in vitro cell culture. However, recent studies, many enabled by new molecular biology techniques, have shown considerable diversity in fibroblast type and function, as described within this volume. Mesenchymal tissue types that are described within include bone, cartilage, tendons and ligaments, muscle, adipose tissue, and skin (dermis). The proper function of these tissues is predominantly dependent upon the proper proliferation, differentiation, and function of the mesenchymal cells which make up the tissue. Recent advancements in primary human mesenchymal cell culture have led to remarkable progress in the study of these tissues. Landmark experiments have now demonstrated a stem cell basis for many of these tissues, and, furthermore, significant plasticity and inter-conversion of stem cells between these tissues, resulting in a great deal of contemporary excitement and controversy. Newly-developed mesenchymal cell culture techniques have even lead to novel clinical practices for the treatment of disease.
Editors and Affiliations
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Oncosis, San Diego, USA
Manfred R. Koller
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Department of Bioengineering, University of California, San Diego, USA
Bernhard O. Palsson
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University College London, London, UK
John R.W. Masters
