Overview
- Provides a comprehensive description of the principle of HS-AFM
- Presents information on devices and techniques to help researchers develop new scanning probe microscopy techniques
- A valuable guide for biologists, biophysicists and bioengineers alike
Part of the book series: NanoScience and Technology (NANO)
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Table of contents (18 chapters)
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Principle and Techniques of HS-AFM
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Biological Applications of HS-AFM
Keywords
About this book
The book is intended to facilitate the first-time use of this new technique, and to inspire students and researchers to tackle their own specific biological problems by directly observing dynamic events occurring in the nanoscopic world. Microscopy in biology has recently entered a new era with the advent of high-speed atomic force microscopy (HS-AFM). Unlike optical microscopy, electron microscopy, and conventional slow AFM, it allows us to directly observe biological molecules in physiological environments. Molecular “movies” created using HS-AFM can directly reveal how molecules behave and operate, without the need for subsequent complex analyses and roundabout interpretations. It also allows us to directly monitor morphological change in live cells, and dynamic molecular events occurring on the surfaces of living bacteria and intracellular organelles. As HS-AFM instruments were recently commercialized, in the near future HS-AFM is expected to become a common tool in biology, and will enhance and accelerate our understanding of biological phenomena.
Authors and Affiliations
Bibliographic Information
Book Title: High-Speed Atomic Force Microscopy in Biology
Book Subtitle: Directly Watching Dynamics of Biomolecules in Action
Authors: Toshio Ando
Series Title: NanoScience and Technology
DOI: https://doi.org/10.1007/978-3-662-64785-1
Publisher: Springer Berlin, Heidelberg
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: Springer-Verlag GmbH Germany, part of Springer Nature 2022
Hardcover ISBN: 978-3-662-64783-7Published: 24 March 2022
eBook ISBN: 978-3-662-64785-1Published: 23 March 2022
Series ISSN: 1434-4904
Series E-ISSN: 2197-7127
Edition Number: 1
Number of Pages: XIX, 319
Number of Illustrations: 10 b/w illustrations, 145 illustrations in colour
Topics: Spectroscopy and Microscopy, Biological and Medical Physics, Biophysics, Cell Cycle Analysis, Biomaterials, Biomedical Engineering and Bioengineering