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Genome Mapping and Genomics in Human and Non-Human Primates

  • Book
  • © 2015

Overview

Editors:
  1. Ravindranath Duggirala

    1. South Texas Diabetes and Obesity Institute, University of Texas Health Science Center at San Antonio, Edinburg, USA

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  2. Laura Almasy

    1. South Texas Diabetes and Obesity Institute, University of Texas Health Science Center at San Antonio, San Antonio, USA

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  3. Sarah Williams-Blangero

    1. South Texas Diabetes and Obesity Institute, Brownsville, USA

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  4. Solomon F.D. Paul

    1. Faculty of Biomedical Sciences, Technology & Research, Sri Ramachandra University, Chennai, India

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  5. Chittaranjan Kole

    1. Bidhan Chandra Krishi Viswavidyalaya, Mohanpur, India

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  • Will be of interest to scientists in the fields of genetics, evolutionary biology, bioinformatics, genetic epidemiology, pharmacogenetics, anthropology and biomedical research
  • Reviews the key genetic sequencing and mapping techniques
  • An invaluable work that will promote further genomic research
  • Includes supplementary material: sn.pub/extras

Part of the book series: Genome Mapping and Genomics in Animals (MAPPANIMAL, volume 5)

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Table of contents (16 chapters)

  1. Front Matter

    Pages i-viii
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  2. The Utility of Genomics for Studying Primate Biology

    • Sarah Williams-Blangero, John Blangero
    Pages 1-6

  3. The Human Genome Project: Where Are We Now and Where Are We Going?

    • Satish Kumar, Christopher Kingsley, Johanna K. DiStefano
    Pages 7-31

  4. Linkage Mapping: Localizing the Genes That Shape Human Variation

    • Laura Almasy, Mark Zlojutro Kos, John Blangero
    Pages 33-52

  5. Association Studies to Map Genes for Disease-Related Traits in Humans

    • Robert L. Hanson, Alka Malhotra
    Pages 53-66

  6. Gene Expression Studies and Complex Diseases

    • Harald H.H. Göring
    Pages 67-83

  7. Copy Number Variations and Chronic Diseases

    • August N. Blackburn, Donna M. Lehman
    Pages 85-101

  8. Applications of Genomic Methods to Studies of Wild Primate Populations

    • Mary A. Kelaita
    Pages 103-112

  9. Comparative Genomics: Tools for Study of Complex Diseases

    • Laura A. Cox
    Pages 113-128

  10. Genetic Structure and Its Implications for Genetic Epidemiology: Aleutian Island Populations

    • Michael H. Crawford
    Pages 129-140

  11. Mapping Genes in Isolated Populations: Lessons from the Old Order Amish

    • Braxton D. Mitchell, Alejandro A. Schäffer, Toni I. Pollin, Elizabeth A. Streeten, Richard B. Horenstein, Nanette I. Steinle et al.
    Pages 141-153

  12. Genetics of Cardiovascular Disease in Minority Populations

    • Jean W. MacCluer, John Blangero, Anthony G. Comuzzie, Sven O. E. Ebbesson, Barbara V. Howard, Shelley A. Cole
    Pages 155-179

  13. Mapping of Susceptibility Genes for Obesity, Type 2 Diabetes, and the Metabolic Syndrome in Human Populations

    • Rector Arya, Sobha Puppala, Vidya S. Farook, Geetha Chittoor, Christopher P. Jenkinson, John Blangero et al.
    Pages 181-245

  14. Genetic Influence on the Human Brain

    • D. Reese McKay, Anderson M. Winkler, Peter Kochunov, Emma E.M. Knowles, Emma Sprooten, Peter T. Fox et al.
    Pages 247-258

  15. Variation, Genetics, and Evolution of the Primate Craniofacial Complex

    • Richard J. Sherwood, Dana L. Duren
    Pages 259-275

  16. Genetic Influences on Behavior in Nonhuman Primates

    • Julia N. Bailey, Christopher Patterson, Lynn A. Fairbanks
    Pages 277-288

  17. Genomic Studies of Human Populations: Resequencing Approaches to the Identification of Human Quantitative Loci

    • Joanne E. Curran, Claire Bellis, Laura Almasy, John Blangero
    Pages 289-299

  18. Back Matter

    Pages 301-305
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Keywords

About this book

This book provides an introduction to the latest gene mapping techniques and their applications in biomedical research and evolutionary biology. It especially highlights the advances made in large-scale genomic sequencing. Results of studies that illustrate how the new approaches have improved our understanding of the genetic basis of complex phenotypes including multifactorial diseases (e.g., cardiovascular disease, type 2 diabetes, and obesity), anatomic characteristics (e.g., the craniofacial complex), and neurological and behavioral phenotypes (e.g., human brain structure and nonhuman primate behavior) are presented.

Topics covered include linkage and association methods, gene expression, copy number variation, next-generation sequencing, comparative genomics, population structure, and a discussion of the Human Genome Project. Further included are discussions of the use of statistical genetic and genetic epidemiologic techniques to decipher the genetic architectureof normal and disease-related complex phenotypes using data from both humans and non-human primates.

Editors and Affiliations

  • South Texas Diabetes and Obesity Institute, University of Texas Health Science Center at San Antonio, Edinburg, USA

    Ravindranath Duggirala

  • South Texas Diabetes and Obesity Institute, University of Texas Health Science Center at San Antonio, San Antonio, USA

    Laura Almasy

  • South Texas Diabetes and Obesity Institute, Brownsville, USA

    Sarah Williams-Blangero

  • Faculty of Biomedical Sciences, Technology & Research, Sri Ramachandra University, Chennai, India

    Solomon F.D. Paul

  • Bidhan Chandra Krishi Viswavidyalaya, Mohanpur, India

    Chittaranjan Kole

Bibliographic Information

  • Book Title: Genome Mapping and Genomics in Human and Non-Human Primates

  • Editors: Ravindranath Duggirala, Laura Almasy, Sarah Williams-Blangero, Solomon F.D. Paul, Chittaranjan Kole

  • Series Title: Genome Mapping and Genomics in Animals

  • DOI: https://doi.org/10.1007/978-3-662-46306-2

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2015

  • Hardcover ISBN: 978-3-662-46305-5Published: 22 April 2015

  • Softcover ISBN: 978-3-662-51839-7Published: 12 October 2016

  • eBook ISBN: 978-3-662-46306-2Published: 25 March 2015

  • Series ISSN: 2512-3394

  • Series E-ISSN: 2512-3408

  • Edition Number: 1

  • Number of Pages: VIII, 305

  • Number of Illustrations: 29 b/w illustrations, 10 illustrations in colour

  • Topics: Animal Genetics and Genomics, Gene Expression, Evolutionary Biology

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