Nucleic Acids and Molecular Biology

1. Front Matter

   Pages I-XI

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2. Laser Raman Spectroscopy of Nucleic Acids

   • G. J. Thomas Jr., A. H.-J. Wang

   Pages 1-30

3. Non-Commensurate Polypurine/Polypyrimidine DNA Structures

   • D. E. Pulleyblank

   Pages 31-48

4. Sequence Specific Recognition of Double Helical DNA. A Synthetic Approach

   • P. B. Dervan

   Pages 49-64

5. Metal Complexes Which Target DNA Sites: Coupling Recognition to Reactivity

   • M. B. Fleisher, H.-Y. Mei, J. K. Barton

   Pages 65-84

6. Mechanistic Studies of Bleomycin-Mediated DNA Cleavage Using Isotope Labeling

   • G. H. McGall, J. Stubbe

   Pages 85-104

7. Oligo-[α]-Deoxyribonucleotides Covalently Linked to Intercalating Agents. A New Family of Sequence-Specific Nucleic Acid Reagents

   • C. Helene, N. T. Thuong

   Pages 105-123

8. The Efficiency of Oligonucleotide-Directed Mutagenesis

   • T. A. Kunkel

   Pages 124-135

9. Protein-Induced DNA Bending

   • A. A. Travers

   Pages 136-148

10. “Zinc Fingers”: A Novel Motif for Nucleic Acid Binding

    • D. Rhodes, A. Klug

    Pages 149-166

11. NMR Studies of Repressor-Operator Interaction. The Lac Control Region

    • R. Kaptein, R. Boelens

    Pages 167-187

12. DNA Repair by the Ada Protein of E. coli

    • P. Karran, J. Hall

    Pages 188-197

13. Homologous Pairing Promoted by Ustilago Rec 1 Protein

    • W. K. Holloman

    Pages 198-205

14. Differential Interaction of the Receptors for Glucocorticoids and Progestins with the Hormone Regulatory Element of MMTV

    • M. Beato, U. Brüggemeier, G. Chalepakis, M. Schauer, E. Slater, T. Willmann

    Pages 206-219

15. Back Matter

    Pages 221-223

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Molecular biology has always been a discipline of rapid development. Despite this, we are presently experiencing a period of unprecedented proliferation of information in nucleic acid studies and molecular biology. These areas are intimately interwoven, so that each influences the other to their mutual benefit. The rapid growth in information leads to ever-increasing specialization, so that it becomes increasingly difficult for a scientist to keep abreast of developments in all the various aspects of the field, although an up-to-date knowledge of the field as a whole is highly desirable. With this background in mind we present the series Nucleic Acids and Molecular Biology. It comprises focused review articles by active researchers who report on the newest developments in their areas of particular interest.

• DNA
• DNA repair
• Nucleotide
• Purine
• Pyrimidine
• biology
• development
• influence
• molecular biology
• nucleic acid
• proliferation
• protein
• receptor
• spectroscopy

• Abteilung Chemie, Max-Planck-Institut für experimentelle Medizin, Göttingen, Germany

  Fritz Eckstein

• Biochemistry Department, University of Dundee, Dundee, UK

  David M. J. Lilley

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