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Mechanical and Chemical Signaling in Angiogenesis

  • Book
  • © 2013

Overview

Editors:
  1. Cynthia A. Reinhart-King

    1. Department of Biomedical Engineering, Cornell Univesity, Ithaca, USA

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  • Gives emphasis to novel methodologies and biomaterials
  • Addresses all biological length scales of angiogenesis: molecular, cellular and tissue in both in vivo and in vitro settings
  • Studies blood vessel growth in tumor formation as well as therapeutic target for the treatment of cardiovascular diseases
  • Written by angiogenesis experts from diverse fields including engineering, cell and developmental biology, chemistry and physics
  • Includes supplementary material: sn.pub/extras

Part of the book series: Studies in Mechanobiology, Tissue Engineering and Biomaterials (SMTEB, volume 12)

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Table of contents (14 chapters)

  1. Front Matter

    Pages i-vi
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  2. Mechanical and Chemical Regulation of Arterial and Venous Specification

    • Thomas N. Sato
    Pages 1-17

  3. Mechanosensory Pathways in Angiocrine Mediated Tissue Regeneration

    • Sina Y. Rabbany, Bi-Sen Ding, Clemence Larroche, Shahin Rafii
    Pages 19-45

  4. Microfluidic Devices for Quantifying the Role of Soluble Gradients in Early Angiogenesis

    • Patrick Benitez, Sarah Heilshorn
    Pages 47-70

  5. Reactive Oxygen Species in Physiologic and Pathologic Angiogenesis

    • Alisa Morss Clyne
    Pages 71-92

  6. Microfluidic Devices for Angiogenesis

    • Vernella Vickerman, Choong Kim, Roger D. Kamm
    Pages 93-120

  7. Vascular Cell Physiology Under Shear Flow: Role of Cell Mechanics and Mechanotransduction

    • Devon Scott, Wei Tan, Jerry S. H. Lee, Owen J. T. McCarty, Monica T. Hinds
    Pages 121-141

  8. Matrix Mechanics and Cell Contractility in Angiogenesis

    • Joseph P. Califano, Cynthia A. Reinhart-King
    Pages 143-160

  9. Computational Modeling of Angiogenesis: Towards a Multi-Scale Understanding of Cell–Cell and Cell–Matrix Interactions

    • Sonja E. M. Boas, Margriet M. Palm, Pieter Koolwijk, Roeland M. H. Merks
    Pages 161-183

  10. ECM Remodeling in Angiogenesis

    • Stephanie J. Grainger, Andrew J. Putnam
    Pages 185-209

  11. Barrier Maintenance in Neovessels

    • Geerten P. van Nieuw Amerongen
    Pages 211-226

  12. Computational Models of Vascularization and Therapy in Tumor Growth

    • Benjamin Ribba, Floriane Lignet, Luigi Preziosi
    Pages 227-246

  13. Biomaterials for Cell-Based Therapeutic Angiogenesis

    • Max H. Rich, Hyunjoon Kong
    Pages 247-259

  14. Translation of Pro-Angiogenic and Anti-Angiogenic Therapies into Clinical Use

    • Sujata K. Bhatia
    Pages 261-278

  15. Erratum to: Reactive Oxygen Species in Physiologic and Pathologic Angiogenesis

    • Krishna Arjunan, Alisa Morss Clyne
    Pages E1-E1

  16. Back Matter

    Pages 279-280
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Keywords

About this book

This volume describes and discusses recent advances in angiogenesis research. The chapters are organized to address all biological length scales of angiogenesis: molecular, cellular and tissue in both in vivo and in vitro settings. Specific emphasis is given to novel methodologies and biomaterials that have been developed and applied to angiogenesis research. Angiogenesis experts from diverse fields including engineering, cell and developmental biology, chemistry and physics will be invited to contribute chapters which focus on the mechanical and chemical signals which affect and promote angiogenesis.

Editors and Affiliations

  • Department of Biomedical Engineering, Cornell Univesity, Ithaca, USA

    Cynthia A. Reinhart-King

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