Neural Tissue Biomechanics

1. Front Matter

   Pages i-viii

   PDF

2. An Introduction to the Biomechanics of the Nervous System

   • Lynne E. Bilston

   Pages 1-9

3. Brain Tissue Mechanical Properties

   • Lynne E. Bilston

   Pages 11-24

4. Spinal Cord Mechanical Properties

   • Elizabeth C. Clarke

   Pages 25-40

5. Constitutive Modelling of Brain Tissue for Prediction of Traumatic Brain Injury

   • J. A. W. van Dommelen, M. Hrapko, G. W. M. Peters

   Pages 41-67

6. Modeling of the Brain for Injury Prevention

   • King H. Yang, Haojie Mao, Christina Wagner, Feng Zhu, Clifford C. Chou, Albert I. King

   Pages 69-120

7. Neural Tissue Biomechanics: Biomechanics and Models of Structural Neurological Disorders

   • Shaokoon Cheng

   Pages 121-134

8. Computational Biomechanics of the Brain; Application to Neuroimage Registration

   • Karol Miller, Adam Wittek, Grand Joldes, Jiajie Ma, Ben Jamin Zwick

   Pages 135-157

9. Biomechanical Aspects of Spinal Cord Injury

   • Thomas R. Oxland, Timothy Bhatnagar, Anthony M. Choo, Marcel F. Dvorak, Wolfram Tetzlaff, Peter A. Cripton

   Pages 159-180

10. Modelling of Spinal Cord Biomechanics: In Vitro and Computational Approaches

    • Cecilia Persson, Jon L. Summers, Richard M. Hall

    Pages 181-201

11. Nerve and Nerve Root Biomechanics

    • Kristen J. Nicholson, Beth A. Winkelstein

    Pages 203-229

12. Mechanotransduction in the Nervous System

    • Lynne E. Bilston, Cheryl L. Stucky

    Pages 231-245

13. In Vitro Models for Biomechanical Studies of Neural Tissues

    • Barclay Morrison III, D. Kacy Cullen, Michelle LaPlaca

    Pages 247-285

14. Back Matter

    Pages 287-288

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Damage to the central nervous system resulting from pathological mechanical loading can occur as a result of trauma or disease. Such injuries lead to significant disability and mortality. The peripheral nervous system, while also subject to injury from trauma and disease, also transduces physiological loading to give rise to sensation, and mechanotransduction is also thought to play a role in neural development and growth. This book gives a complete and quantitative description of the fundamental mechanical properties of neural tissues, and their responses to both physiological and pathological loading. This book reviews the methods used to characterize the nonlinear viscoelastic properties of central and peripheral neural tissues, and the mathematical and sophisticated computational models used to describe this behaviour. Mechanisms and models of neural injury from both trauma and disease are reviewed from the molecular to macroscopic scale. The book provides a comprehensive picture of the mechanical and biological response of neural tissues to the full spectrum of mechanical loading to which they are exposed. This book provides a comprehensive reference for professionals involved in pre prevention of injury to the nervous system, whether this arises from trauma or disease.

• Brain injury
• Neural mechanotransduction
• Neural tissue repair and regeneration
• Peripheral nerve injury
• Spinal cord injury
• Structural disorders of the nervous system
• Tissue biomechanics
• Viscoelasticity

From the reviews:

“This textbook discusses the biomechanics of brain and spinal cord injuries inc. trauma via blunt force, tumors, & hemorrhage. … This book has an international authorship and will be requisite studies for neurosurgeons, orthopaedics, and neurologists. It will be appropriate for graduate students as well.” (Joseph J. Grenier, Amazon.com, December, 2013)

• Medical Research Institute, Prince of Wales, Randwick, Australia

  Lynne E. Bilston

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