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Extracellular Nucleic Acids

  • Book
  • © 2010

Overview

Editors:
  1. Yo Kikuchi

    1. , Dept. of Environmental and Life Sciences, Toyohashi University of Technology, Toyohashi-city, Japan

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    You can also search for this editor in PubMed   Google Scholar

  2. Elena Y. Rykova

    1. Fundamental Medicine, Institute of Chemical Biology and, Novosibirsk, Russian Federation

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • First comprehensive coverage of this newly emerging field
  • Spans related fields from basic biology to medical sciences
  • Written by experts working on the forefront of the field

Part of the book series: Nucleic Acids and Molecular Biology (NUCLEIC, volume 25)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xi
    Download chapter PDF

  2. Extracellular DNA as Matrix Component in Microbial Biofilms

    • Wen-Chi Chiang, Tim Tolker-Nielsen
    Pages 1-14

  3. Gene Transfer Agents and Defective Bacteriophages as Sources of Extracellular Prokaryotic DNA

    • Andrew S. Lang, J. Thomas Beatty
    Pages 15-24

  4. Roles of Extracellular DNA in Bacterial Ecosystem

    • Katsuji Tani, Masao Nasu
    Pages 25-37

  5. Stable Extracellular DNA: A Novel Substrate for Genetic Engineering that Mimics Horizontal Gene Transfer in Nature

    • Shinya Kaneko, Mitsuhiro Itaya
    Pages 39-53

  6. Extracellular Nucleic Acids of the Marine Phototrophic Bacterium Rhodovulum sulfidophilum and Related Bacteria: Physiology and Biotechnology

    • Yo Kikuchi
    Pages 55-67

  7. Systemic RNAi in C. elegans from the Viewpoint of RNA as Extracellular Signals

    • Lisa Timmons
    Pages 69-92

  8. Circulating Nucleic Acids in Health and Disease

    • E. Y. Rykova, P. P. Laktionov, V. V. Vlassov
    Pages 93-128

  9. Circulating MicroRNAs in Cancer

    • Patrick S. Mitchell, Muneesh Tewari
    Pages 129-145

  10. Biology and Diagnostic Applications of Cell-Free Fetal Nucleic Acids in Maternal Plasma

    • Jason C. H. Tsang, Y. M. Dennis Lo
    Pages 147-166

  11. The Biology of Circulating Nucleic Acids in Plasma and Serum (CNAPS)

    • P. B. Gahan, M. Stroun
    Pages 167-189

  12. Modulation and Regulation of Gene Expression by CpG Oligonucleotides

    • Dennis Klinman, Sven Klaschik
    Pages 191-208

  13. Immune Recognition of Nucleic Acids and Their Metabolites

    • Shohei Koyama, Shizuo Akira, Ken J. Ishii
    Pages 209-227

  14. Back Matter

    Pages 229-232
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Keywords

About this book

Extracellular nucleic acids have recently emerged as important players in the fields of biology and the medical sciences. In the last several years, extracellular nucleic acids have been shown to be involved in not only microbial evolution as genetic elements but also to have structural roles in bacterial communities, such as biofilms. Circulating DNA and RNA have been found in human blood and expected to be useful as non-invasive markers for the diagnosis of several diseases. In addition, extracellular nucleic acids have attracted attention as active modulators of the immune system of higher organisms, including humans. This book covers nearly all of the newly developing fields related to extracellular nucleic acids, including those of basic biology, ecology and the medical sciences, and provides readers with the latest knowledge on them.

Editors and Affiliations

  • , Dept. of Environmental and Life Sciences, Toyohashi University of Technology, Toyohashi-city, Japan

    Yo Kikuchi

  • Fundamental Medicine, Institute of Chemical Biology and, Novosibirsk, Russian Federation

    Elena Y. Rykova

Bibliographic Information

  • Book Title: Extracellular Nucleic Acids

  • Editors: Yo Kikuchi, Elena Y. Rykova

  • Series Title: Nucleic Acids and Molecular Biology

  • DOI: https://doi.org/10.1007/978-3-642-12617-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer-Verlag Berlin Heidelberg 2010

  • Hardcover ISBN: 978-3-642-12616-1Published: 31 July 2010

  • Softcover ISBN: 978-3-642-26419-1Published: 05 September 2012

  • eBook ISBN: 978-3-642-12617-8Published: 23 July 2010

  • Series ISSN: 0933-1891

  • Series E-ISSN: 1869-2486

  • Edition Number: 1

  • Number of Pages: XII, 232

  • Number of Illustrations: 34 b/w illustrations

  • Topics: Cell Biology, Biochemistry, general

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