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  • Book
  • © 2004

Practical Bioinformatics

  • Unique feature of this book is its interdisciplinary approach: it combines computational (theoretical) and experimental approaches to solve non-trivial scientific problems
  • First book to focus on the application of bioinformatic tools for protein sequence-structure-function analysis
  • Includes supplementary material: sn.pub/extras

Part of the book series: Nucleic Acids and Molecular Biology (NUCLEIC, volume 15)

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Table of contents (11 chapters)

  1. Front Matter

    Pages I-XVII
  2. Computational Methods for Protein Structure Prediction and Fold Recognition

    • Iwona A. Cymerman, Marcin Feder, Marcin PawŁowski, Michal A. Kurowski, Janusz M. Bujnicki
    Pages 1-21
  3. ‘Meta’Approaches to Protein Structure Prediction

    • Janusz M. Bujnicki, Daniel Fischer
    Pages 23-34
  4. From Molecular Modeling to Drug Design

    • Martin Cohen-Gonsaud, Vincent Catherinot, Gilles Labesse, Dominique Douguet
    Pages 35-71
  5. Structure Determination of Macromolecular Complexes by Experiment and Computation

    • Frank Alber, Narayanan Eswar, Andrej Sali
    Pages 73-96
  6. Modeling Protein Folding Pathways

    • Christopher Bystroff, Yu Shao
    Pages 97-122
  7. Structural Bioinformatics and NMR Structure Determination

    • Jens P. Linge, Michael Nilges
    Pages 123-137
  8. Bioinformatics-Guided Identification and Experimental Characterization of Novel RNA Methyltransferas

    • Janusz M. Bujnicki, Louis Droogmans, Henri Grosjean, Suresh K. Purushothaman, Bruno Lapeyre
    Pages 139-168
  9. Back Matter

    Pages 263-265

About this book

The book is unique in that it bridges the gap between bioinformaticists and molecular biologists, i.e. the developers and the users of computational methods for biological data analysis and in that it presents examples of practical applications of the bioinformatics tools in the "daily practice" of an experimental research scientist.

The book starts with reviews on computational methods for protein sequence-structure-function analysis (sequence studies, structure prediction), followed by methods that explicitly utilize experimental data routinely obtained in the laboratory to improve the functional predictions. The second part comprises a series of examples on how particular applications of different types of bioinformatics methods in combination with experimental studies to validate the hypotheses have led to important scientific discoveries.

Therefore, the book is a guide to application of bioinformatics methods in molecular biology, addressed mainly to researchscientists, postdocs, and advanced graduate students.

Editors and Affiliations

  • International Institute of Molecular and Cell Biology in Warsaw, Warsaw, Poland

    Janusz M. Bujnicki

Bibliographic Information

Buy it now

Buying options

eBook USD 129.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access