Skip to main content
SpringerLink
Log in

Cushing’s Syndrome

  • Book
  • © 1982

Overview

Authors:
  1. Dorothy T. Krieger

    1. Division of Endocrinology, The Mount Sinai Medical Center, New York, USA

    View author publications

    You can also search for this author in PubMed   Google Scholar

Part of the book series: Monographs on Endocrinology (ENDOCRINOLOGY, volume 22)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 16.99 USD 84.99
Discount applied Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (8 chapters)

  1. Front Matter

    Pages I-IX
    Download chapter PDF

  2. Brief Introduction to Cushing’s Syndrome and Disease

    • Dorothy T. Krieger
    Pages 1-4

  3. Physiology of Regulation of ACTH Secretion

    • Dorothy T. Krieger
    Pages 5-22

  4. ACTH Action

    • Dorothy T. Krieger
    Pages 23-32

  5. Actions of Adrenocortical Hormones

    • Dorothy T. Krieger
    Pages 33-39

  6. The Nature of ACTH-Related Peptides in Cushing’s Disease and Syndrome

    • Dorothy T. Krieger
    Pages 40-43

  7. Clinical Manifestations of Cushing’s Disease and Cushing’s Syndrome

    • Dorothy T. Krieger
    Pages 44-72

  8. Laboratory Diagnosis of Cushing’s Disease and Syndrome

    • Dorothy T. Krieger
    Pages 73-118

  9. Treatment of Cushing’s Disease and Syndrome

    • Dorothy T. Krieger
    Pages 119-137

  10. Back Matter

    Pages 139-142
    Download chapter PDF
Back to top

Keywords

About this book

The unraveling of our knowledge of the functions of the adrenal gland constitutes one exciting development of modern medicine and biochemistry. We owe these advances to the felicitous cooperative efforts of the clinical investigator and the biochemist. Three centuries elapsed between the first recorded anatomical descrip­ tion of the adrenals and the demonstration by Dr. Addison in the mid-nineteenth century of the fatal results of the destruction of these glands by disease. It became evident from this observation that the adrenals secreted a "factor" or "factors" essential to life. It took approximately 90 years to isolate this elusive vital factor - cortisone - from beef adrenal cortices, independently by both Reichstein and his co-workers in Basle and Kendall and his group in the United States and another 10-15 years before it became more generally available for experimental and clinical use. It is perhaps difficult to believe that as recently as 35-40 years ago, before cortisone and cortisol were clinically available, the surgical removal of a benign adrenal cortical tumor in patients with Cushing's syndrome was associated with a prohibitive postoperative mortality rate. Within 12-36 h after operation, most of such patients developed an intractable state of shock, which was not manifested by significant electrolyte abnormalities or hypoglycemia and was unresponsive to the usual treatment for shock plus the generous use of salt-retaining hormone.

Authors and Affiliations

  • Division of Endocrinology, The Mount Sinai Medical Center, New York, USA

    Dorothy T. Krieger

Bibliographic Information

  • Book Title: Cushing’s Syndrome

  • Authors: Dorothy T. Krieger

  • Series Title: Monographs on Endocrinology

  • DOI: https://doi.org/10.1007/978-3-642-81659-8

  • Publisher: Springer Berlin, Heidelberg

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer-Verlag Berlin, Heidelberg 1982

  • Softcover ISBN: 978-3-642-81661-1Published: 07 January 2012

  • eBook ISBN: 978-3-642-81659-8Published: 06 December 2012

  • Series ISSN: 0077-1015

  • Edition Number: 1

  • Number of Pages: X, 144

  • Number of Illustrations: 9 b/w illustrations

  • Topics: Endocrinology

Publish with us

Policies and ethics

Back to top

Search

Navigation