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  • Book
  • © 2016

Modified Nucleic Acids

  • Summarizes the latest studies in modified nucleic acid research
  • Spans various aspects of modified nucleic acids, from their chemical synthesis to the in vivo application
  • Written by internationally respected experts

Part of the book series: Nucleic Acids and Molecular Biology (NUCLEIC, volume 31)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-x
  2. Emissive 5-Substituted Uridine Analogues

    • Andrea Fin, Alexander R. Rovira, Patrycja A. Hopkins, Yitzhak Tor
    Pages 1-26
  3. Fluorescent Purine Nucleosides and Their Applications

    • Yoshio Saito, Azusa Suzuki, Isao Saito
    Pages 27-61
  4. Synthetic Wavelength-Shifting Fluorescent Probes of Nucleic Acids

    • Christian Schwechheimer, Marcus Merkel, Peggy R. Bohländer, Hans-Achim Wagenknecht
    Pages 83-100
  5. DNA-Assisted Multichromophore Assembly

    • Tadao Takada, Mitsunobu Nakamura, Kazushige Yamana
    Pages 101-121
  6. Polymerase Synthesis of Base-Modified DNA

    • Jitka Dadová, Hana Cahová, Michal Hocek
    Pages 123-144
  7. Photo-Cross-Linking Reaction in Nucleic Acids: Chemistry and Applications

    • Takashi Sakamoto, Kenzo Fujimoto
    Pages 145-157
  8. Site-Directed Spin Labeling for EPR Studies of Nucleic Acids

    • Sandip A. Shelke, Snorri Th. Sigurdsson
    Pages 159-187
  9. Genetic Alphabet Expansion by Unnatural Base Pair Creation and Its Application to High-Affinity DNA Aptamers

    • Michiko Kimoto, Ken-ichiro Matsunaga, Yushi T. Redhead, Ichiro Hirao
    Pages 249-268
  10. Back Matter

    Pages 269-276

About this book

This book spans diverse aspects of modified nucleic acids, from chemical synthesis and spectroscopy to in vivo applications, and highlights studies on chemical modifications of the backbone and nucleobases. Topics discussed include fluorescent pyrimidine and purine analogs, enzymatic approaches to the preparation of modified nucleic acids, emission and electron paramagnetic resonance (EPR) spectroscopy for studying nucleic acid structure and dynamics, non-covalent binding of low- and high-MW ligands to nucleic acids and the design of unnatural base pairs. This unique book addresses new developments and is designed for graduate level and professional research purposes.

Editors and Affiliations

  • The Institute of Scientific and Industri, Osaka University, Ibaraki, Osaka, Japan

    Kazuhiko Nakatani

  • University of California, San Diego, La Jolla, USA

    Yitzhak Tor

Bibliographic Information

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access