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Drug Treatment of Sleep Disorders

  • Book
  • © 2015

Overview

  • Maximizes reader insights into recent breakthrough in drug treatment
  • Describes drug development from bench to clinic
  • Treats both basic research and clinical applications
  • Includes supplementary material: sn.pub/extras

Part of the book series: Milestones in Drug Therapy (MDT)

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Table of contents (14 chapters)

  1. General Concepts

  2. Drugs to Treat Insomnia

  3. Drugs to Treat Excessive Daytime Sleepiness

  4. Drugs to Treat Circadian Sleep Disorders

  5. Conclusive Remarks

Keywords

About this book

Following reviews on sleep physiology, regulation, pharmacology, and the neuronal networks regulating sleep and awakening, as well as a classification of sleep disorders, this book presents a number of major breakthroughs in the treatment of those disorders. These include recently approved drugs for treating insomnia, such as Doxepin; variations on previously approved molecules, e.g. Zolpidem sublingual preparation; or new chemical entities in advanced stages of clinical development, e.g. Orexin antagonists. Further topics discussed include drugs acting on the GABA receptor, such as Lorediplon and Eszopiclone; the treatment of excessive daytime drowsiness with cell therapy and drugs such as Modafinil, Armodafinil and Sodium oxybate; and the use of Tasimelteon in the treatment of circadian sleep disorders.

Reviews

“This book explores major breakthroughs in the drug treatment of sleep disorders. … The intended audience is scientists, clinicians, and drug developers. … With its specific aim of providing an extensive update on drug treatment for sleep disorders, this book is helpful contribution to sleep medicine.” (M. Isabel L. Crisostomo, Doody’s Book Reviews, July, 2015)

Editors and Affiliations

  • Independent Pharmaceutical Consultant, Barcelona, Spain

    Antonio Guglietta

Bibliographic Information

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