Overview
- Presents the first book on engram cells
- Covers the molecular, cellular, circuit, and systems-level neuroscience of memory engrams
- Explores how engram cells contribute to information encoding and storage across diverse brain regions and behaviors
Part of the book series: Advances in Neurobiology (NEUROBIOL, volume 38)
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About this book
This is the first book to extensively explore the current state-of-the-art and promise of engram cells, the closest physical approximation of the memory trace to date. Converging evidence suggests that memories are stored, at least in part, as specific populations of engram cells. In this book, the leading experts in engram biology share their continuously refined insights on how engram cells contribute to information encoding and storage, across diverse brain regions and behavioral modalities. “Engrams: A Window into the Memory Trace" is broad in scope and spans molecular, cellular, circuit, computational as well as societal-philosophical aspects of memory engrams. Particular emphasis is placed on their emerging translational value for memory dysfunctions in age and stress-related disorders.
Keywords
- engrams
- memory
- learning
- neurobiology
- optogenetics
- chemogenetics
Editors and Affiliations
About the editors
Johannes Gräff, PhD, is Associate Professor and Director of the Laboratory of Neuroepigenetics at the Brain Mind Institute of the Ecole Polytechnique Federale de Lausanne (EPFL) in Lausanne, Switzerland. Trained as a biologist at the University of Lausanne, Johannes Gräff obtained his PhD in Neuroscience at ETH Zurich before pursuing his postdoctoral studies at the Picower Institute of Learning and Memory at the Massachusetts Institute of Technology in Boston, USA. His laboratory studies the molecular underpinnings of memory formation, storage and change, with a particular emphasis on epigenetic mechanisms.
Steve Ramirez is an Associate Professor of Psychological and Brain Sciences at Boston University and a former Junior Fellow of Harvard University. He received his B.A. in neuroscience from Boston University and went on to receive his Ph.D. in neuroscience at MIT. His lab focuses on imaging and manipulating memories throughout the mammalian brain, with a particular emphasis on artificially modulating memories to alleviate symptoms associated with pathologies of the brain.
Bibliographic Information
Book Title: Engrams
Book Subtitle: A Window into the Memory Trace
Editors: Johannes Gräff, Steve Ramirez
Series Title: Advances in Neurobiology
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2024
Hardcover ISBN: 978-3-031-62982-2Due: 30 August 2024
Softcover ISBN: 978-3-031-62985-3Due: 30 August 2024
eBook ISBN: 978-3-031-62983-9Due: 30 August 2024
Series ISSN: 2190-5215
Series E-ISSN: 2190-5223
Edition Number: 1
Number of Pages: X, 328
Number of Illustrations: 2 b/w illustrations, 32 illustrations in colour