Overview
- Covers a wide range of topics, including transcriptomics, immunology, pathogenesis, modeling
- Provides a broad overview of systems biology and its applications in various fields
- Improves understanding of the principles of cell and tissue organisation
Part of the book series: RNA Technologies (RNATECHN, volume 15)
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About this book
Modern biology is moving away from reductionist approaches towards holistic studies that encompass whole genomes, transcriptomes, proteomes, and metabolomes. Systems biology is an approach to studying complex biological systems by looking at many biomolecules in a comprehensive way. The aim is to gain a thorough understanding of the biological functions of different classes of molecules and their interactions.
Systems Biology II is an up-to-date and comprehensive guide to the latest developments in systems biology, with a particular focus on RNA-based technologies. This book is the second volume in the RNA Technologies series dedicated to this topic. It presents cutting-edge approaches and tools for modelling and analyzing complex biological systems at different levels, from molecular interactions to cellular networks and beyond.
With contributions from leading experts in the field, the book covers a wide range of topics, including gene regulatory networks, epigenetics, synthetic biology, omics data analysis, network inference, and more. It explores applications in various areas of the life sciences and biomedicine, such as vaccine development, cancer research, transplantation research and pathogenic processes.
This volume is an essential resource for scientists and students working in systems biology, bioinformatics, synthetic biology, and related fields, as well as anyone interested in the latest advances in RNA technologies and their applications in biology and medicine.
Keywords
- Biological Networks
- Cancer
- Complex Diseases
- Complex Systems Analysis
- Modeling in Systems Biology
- Modeling in Systems Medicine
- System Biology Methods
- Vaccine Development
Editors and Affiliations
About the editor
Jan Barciszewski is Professor at Adam Mickiewicz University (AMU) in Poznań, Poland, and at the Institute of Bioorganic Chemistry of the Polish Academy of Sciences, Poznań, Poland, where he has worked since 1974. He studied organic chemistry at the AMU. During his Ph.D. studies, he worked on the structure and function of modified bases and nucleoside sequences of plant phenylalanine-specific transfer ribonucleic acid (tRNA), including cytokinins. He was subsequently granted Doctor of Science degree for his work on the properties of plant tRNAs and aminoacyl-tRNA synthetases. In the 1990s, he began working on the diagnosis and therapy of brain tumors. He developed a new method for the transformation of plant mitochondria based on catalytic RNAs and is currently involved in studies on a new type of catalytic RNAs (enantiomeric ribozymes) for efficient RNA target cleavage in vivo, as well as the search for new anti-aging agents.
Bibliographic Information
Book Title: Systems Biology II
Editors: Jan Barciszewski
Series Title: RNA Technologies
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2024
Hardcover ISBN: 978-3-031-62177-2Due: 31 August 2024
Softcover ISBN: 978-3-031-62180-2Due: 31 August 2024
eBook ISBN: 978-3-031-62178-9Due: 31 August 2024
Series ISSN: 2197-9731
Series E-ISSN: 2197-9758
Edition Number: 1
Number of Pages: X, 340
Number of Illustrations: 50 illustrations in colour