Overview
- Gives overview on the formation and function of multinuclear cells (syncytia)
- Presents molecular and cellular aspects of syncytia in various organisms
- Covers naturally occurring and disease-induced syncytia
Part of the book series: Results and Problems in Cell Differentiation (RESULTS, volume 71)
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Table of contents (21 chapters)
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Front Matter
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Germline Syncytia, Evolution, Function, and Structure
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Front Matter
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Syncytia in Embryogenesis and Development
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Front Matter
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Fungal and Somatic Cell Syncytia and Genomic View of Extremophiles as the Ancestral Precursors of Eukaryotic Syncytia
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Front Matter
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Virus- and Parasite-Induced Syncytia
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Front Matter
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Keywords
About this book
This book gives a current overview on the development, origin, structure, and functions of germline and somatic cell syncytia during embryogenesis and organogenesis. It also reviews pathogen-induced syncytia and the role of syncytial cells in cancer development.
The book covers the following topics:
- germline syncytia, evolution, function and structure;
- syncytia in embryogenesis and development;
- the role of somatic cell fusion in fungi, specialized somatic tissues, host defense and adaptation;
- syncytia induced by viruses and parasites;
- syncytia and circulating hybrid cells in cancer and other pathological conditions;
It also discusses how the genomic adaptations of microorganisms to extreme habitats can prompt the evolution of mononuclear and multinucleate/syncytial cells.
The book offers a fresh outlook on syncytia's role in various processes: embryogenesis, organogenesis, adaptation, host defense, and development of specialized tissues. It highlights the importance of syncytia under physiological and pathological conditions.
Editors and Affiliations
About the editors
Ahmed Uosef finished his medical degree (MD) at the Ain Shams University Faculty of Medicine in Egypt in 2016. Since 2016 he participated in the clinical rotations at the Houston Methodist Hospital Surgical Liver ICU, gastroenterology at Baylor College of Medicine, St. Luke's Center, Houston, TX, Cardiovascular and Thoracic Surgery at Texas Heart Institute, St. Luke's Medical Center, Houston, TX. Presently he is a postdoctoral fellow at the Houston Methodist Hospital and Houston Methodist Academic Institute, Houston, TX, USA. During his postdoctoral work he has been involved in the basic and translation research on the role of macrophages in the development of chronic rejection of transplanted organs. His interests focus on the molecular and organellar aspects, and the involvement of the actin cytoskeleton and RhoA pathway in shaping macrophage response to the immune challenges.
Bibliographic Information
Book Title: Syncytia: Origin, Structure, and Functions
Editors: Malgorzata Kloc, Ahmed Uosef
Series Title: Results and Problems in Cell Differentiation
DOI: https://doi.org/10.1007/978-3-031-37936-9
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exlusive licence to Springer Nature Switzerland AG 2024
Hardcover ISBN: 978-3-031-37935-2Published: 24 November 2023
Softcover ISBN: 978-3-031-37938-3Due: 25 December 2023
eBook ISBN: 978-3-031-37936-9Published: 23 November 2023
Series ISSN: 0080-1844
Series E-ISSN: 1861-0412
Edition Number: 1
Number of Pages: X, 485
Number of Illustrations: 11 b/w illustrations, 70 illustrations in colour
Topics: Developmental Biology, Stem Cells, Cell Biology, Cell Biology