Overview
- Editors:
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Zhao-Wen Wang
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Department of Neuroscience, University of Connecticut School of Medicine, Farmington, USA
- Presents up-to-date, in-depth coverage of molecular mechanisms of neurotransmitter release
- Offers a wealth of color illustrations and diagrams to demonstrate key concepts
- Provides new chapters on calcium sensors, complexins, tomosyn, and several other presynaptic regulators
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Table of contents (14 chapters)
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- Xin-Sheng Wu, Ling-Gang Wu
Pages 43-62
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- Mark T. Palfreyman, Sam E. West, Erik M. Jorgensen
Pages 63-118
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- Zhao-Wen Wang, Sadaf Riaz, Longgang Niu
Pages 139-170
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- Frédéric A. Meunier, Zhitao Hu
Pages 203-231
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- Chun Hin Chow, Mengjia Huang, Shuzo Sugita
Pages 233-254
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- Francisco José López-Murcia, Kerstin Reim, Holger Taschenberger
Pages 255-285
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- Zhao-Wen Wang, Longgang Niu, Sadaf Riaz
Pages 287-304
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- Zhao-Wen Wang, Laurence O. Trussell, Kiranmayi Vedantham
Pages 305-331
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- Motokazu Uchigashima, Yasunori Hayashi, Kensuke Futai
Pages 333-356
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- Isaac O. Akefe, Shona L. Osborne, Benjamin Matthews, Tristan P. Wallis, Frédéric A. Meunier
Pages 357-397
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Back Matter
Pages 399-401
About this book
Neurons communicate with each other by releasing neurotransmitters. This book provides comprehensive coverage of the molecular mechanisms involved in neurotransmitter release. The topics covered in the book range from the architecture and cytomatrix proteins of presynaptic sites, to the modes of synaptic vesicle exocytosis (full-collapse and kiss-and-run), and from the key molecules mediating synaptic vesicle fusion (SNAREs) to those that closely interact with them (UNC-13/Munc13, UNC-18/Munc18, tomosyn, and complexins). The book also delves into the calcium sensors of synaptic vesicle fusion (synaptotagmins and Doc2s), the sources of calcium that trigger synaptic exocytosis (voltage-gated calcium channels and ryanodine receptors), and the regulation of neurotransmitter release by potassium channels, cell adhesion molecules, lipids, aryl hydrocarbon receptor-interacting protein (AIP), presenilins, and calstabins. To aid in understanding and illustrate key concepts, the book includes sufficient background information and a wealth of illustrations and diagrams. The new edition includes major updates to previous chapters, as well as several new chapters that reflect the recent advances in the field. Comprehensive and cutting-edge, Molecular Mechanisms of Neurotransmitter Release, 2nd edition, is a valuable learning resource for neuroscience students and a solid reference for neuroscientists.
Editors and Affiliations
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Department of Neuroscience, University of Connecticut School of Medicine, Farmington, USA
Zhao-Wen Wang
About the editor
​Zhao-Wen Wang, PhD, is Professor of Neuroscience in the Faculty of Neuroscience, Cell Biology, and Genetics and Developmental Biology, University of Connecticut Health Center, Farmington, Connecticut. His major research interests are on the functions and regulation of the BK channel and gap junctions, and molecular mechanisms of neurotransmitter release.
