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Nano- and Microfabrication Techniques in Drug Delivery

Recent Developments and Future Prospects

  • Book
  • © 2023

Overview

Editors:
  1. Dimitrios Lamprou

    1. School of Pharmacy, Queen’s University Belfast, Belfast, UK

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  • Brings together technical, clinical, regulatory and industrial perspectives
  • Provides future prospective and includes the potential clinical applications of nano/microfabrication technologies
  • Appeals to a broad readership, such as materials scientists, pharmaceutical engineers, clinicians and regulatory experts

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Table of contents (17 chapters)

  1. Front Matter

    Pages i-xiii
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  2. Conducting Polymers as Drug Release Systems

    • James R. Smith
    Pages 1-19

  3. Electrospinning for Drug Delivery Applications

    • Luis Jesús Villarreal-Gómez, Graciela Lizeth Pérez-González
    Pages 21-40

  4. Melt Electrospinning and Electrowriting for Pharmaceutical and Biomedical Applications

    • María del Carmen De Lama-Odría, Luis J. del Valle, Jordi Puiggalí
    Pages 41-70

  5. Pharmaceutical Spray Drying

    • Ioannis Partheniadis, Nizar Al-Zoubi, Ioannis Nikolakakis
    Pages 71-97

  6. Vat Photopolymerisation Additive Manufacturing for Pharmaceutical Applications

    • Atheer Awad, Xiaoyan Xu, Jun Jie Ong, Alvaro Goyanes, Abdul W. Basit
    Pages 99-124

  7. Semi-solid Extrusion 3D Printing for the Development of Dosage Forms for Special Patient Groups

    • Angelos Gkaragkounis, Dimitrios G. Fatouros
    Pages 125-136

  8. Binder Jetting Powder Bed 3D Printing for the Fabrication of Drug Delivery System

    • Naseem A. Charoo, Eman M. Mohamed, Mathew Kuttolamadom, Mansoor A. Khan, Ziyaur Rahman
    Pages 137-172

  9. 3D Printing for Localized Cancer Therapy

    • Mahmood Razzaghi, Amir Seyfoori, Mohsen Akbari
    Pages 173-205

  10. 4D Printing in Pharmaceutics and Biomedical Applications

    • Moqaddaseh Afzali Naniz, Mohsen Askari, Ali Zolfagharian, Mahdi Bodaghi
    Pages 207-247

  11. Lithography in Drug Delivery

    • Khanh T. M. Tran, Thanh D. Nguyen
    Pages 249-274

  12. Micro-molding and Its Application to Drug Delivery

    • Edina Vranić
    Pages 275-294

  13. Supercritical Fluids: A Promising Technique in Pharmaceutics

    • Vivek Trivedi, Adejumoke Lara Ajiboye
    Pages 295-320

  14. Microfluidics as a Tool for the Synthesis of Advanced Drug Delivery Systems

    • João P. Martins, Hélder A. Santos
    Pages 321-364

  15. Nanofluidic Technologies for Drug Screening and Drug Delivery

    • Yutaka Kazoe, Kenji Sueyoshi, Sasikarn Seetasang, Yan Xu
    Pages 365-418

  16. Nanoparticles at the Stage of Clinical Trials

    • Konstantin Osetrov, Svetlana Morozkina, Petr Snetkov, Mayya Uspenskaya
    Pages 419-428

  17. Nasal Drug Delivery Systems for the Treatment of Diseases of the Central Nervous System and Tuberculosis

    • Thi Hong Nhung Vu, Svetlana Morozkina, Petr Snetkov, Mayya Uspenskaya
    Pages 429-466

  18. Regulatory Aspects and Barriers in Using Groundbreaking Technologies

    • Paola Minghetti, Umberto M. Musazzi, Paolo Rocco
    Pages 467-491
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Keywords

About this book

New materials and manufacturing techniques are evolving with the potential to address the challenges associated with the manufacture of medicinal products that will teach new tricks to old drugs. Nano- and microfabrication techniques include manufacturing methods such as additive manufacturing, lithography, micro-moulding, spray drying, and supercritical fluids among many others. The increasing resolution of new techniques allow researchers to produce objects with micrometric resolutions. This book follows a consecutive order, beginning with a background in the current field and limitations in the manufacturing of different pharmaceutical products, moving on the classification of each method by providing recent examples, and future prospective on a variety of traditional and new Nano and microfabrication techniques. A focus on the materials used to prepare these systems and their biocompatibility, including applied topics such as clinical applications and regulatory aspects also covered, offering the reader a holistic view of this rapidly growing field.

Editors and Affiliations

  • School of Pharmacy, Queen’s University Belfast, Belfast, UK

    Dimitrios Lamprou

About the editor

Dimitrios Lamprou (Ph.D., MBA) is Professor (Chair) of Biofabrication and Advanced Manufacturing at Queen’s University Belfast. Prof Lamprou lab is applying Nano and Microfabrication Techniques in the Manufacturing of Drug Delivery Systems, Medical Devices & Implants. He has trained in multidisciplinary areas, worked in projects across disciplines, and in first class laboratories in a number of countries. To date, he has over 130 peer-reviewed publications in leading international journals and over 350 conference abstracts, and has over 130 Oral Talks in the area of Nano/Microfabrication.

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