Editors:
- Covers the historical development of clinical ageing research
- Addresses the biochemistry and cell biology of aging from a clinical perspective
- Discusses how various organs and tissues are affected by ageing events
Part of the book series: Subcellular Biochemistry (SCBI, volume 103)
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Table of contents (16 chapters)
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Front Matter
About this book
This book provides an up-to-date overview of key areas of ageing research and bridges the gap between the subcellular events and the reality of ageing as seen in clinical practice.
To this end, the reader learns about the historical development and progression of clinical ageing research. All chapters address the biochemistry or cell biology of various ageing events (to the extent that the data are available) and work their way to the clinical understanding we have of ageing. The focus of this volume is on how dietary restriction, virus infection and chronic inflammation affect the ageing process. Additionally, this book discusses how phosphate metabolism and metabolic dysfunction contribute to ageing events and how various organs and tissues (e.g. tendons, ears, heart muscle, and the endocrine system) age.
This book follows on from Parts I, II and III of Biochemistry and Cell Biology of Ageing within the Subcellular Biochemistry book series and aims to bring the subcellular and clinical areas into closer contact by including interesting and significant biomedical ageing topics that were not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
Editors and Affiliations
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Institute for Molecular Physiology, University of Mainz, Mainz, Germany
J. Robin Harris
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Biosciences Institute, Newcastle University, Newcastle upon Tyne, UK
Viktor I. Korolchuk
About the editors
reflected in the diversity of content of the Series.
Viktor I. Korolchuk is Reader in Molecular Cell Biology at Newcastle University. His scientific interests lie in the area of intracellular protein trafficking and degradation pathways. The current focus of research in his laboratory is autophagy (literally self-eating) where portions of cytoplasm are recruited into intracellular vesicles called autophagosomes and transported for degradation by lysosomal hydrolases.
Bibliographic Information
Book Title: Biochemistry and Cell Biology of Ageing: Part IV, Clinical Science
Editors: J. Robin Harris, Viktor I. Korolchuk
Series Title: Subcellular Biochemistry
DOI: https://doi.org/10.1007/978-3-031-26576-1
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023
Hardcover ISBN: 978-3-031-26575-4Published: 30 April 2023
Softcover ISBN: 978-3-031-26578-5Due: 31 May 2023
eBook ISBN: 978-3-031-26576-1Published: 29 April 2023
Series ISSN: 0306-0225
Series E-ISSN: 2542-8810
Edition Number: 1
Number of Pages: VIII, 458
Number of Illustrations: 2 b/w illustrations, 46 illustrations in colour
Topics: Aging, Cell Biology, Medical Biochemistry, Protein Science