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Basic and Translational Applications of the Network Theory for Dystonia

  • Book
  • © 2023

Overview

  • Discusses new findings in dystonia research
  • Provides information on the network theory of dystonia
  • Resource for those studying movement disorders and motor control

Part of the book series: Advances in Neurobiology (NEUROBIOL, volume 31)

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Table of contents (13 chapters)

Keywords

About this book

A recently proposed novel scheme of dystonia suggests that it is a disorder of neural network.  Impairment in any of the “nodes” of the network may result in deficient network activity, causing dystonia.  This book aims to present various experimental evidence supporting the network theory of dystonia.  Dystonia is the abnormal twisting and turning of the organ and associated involuntary oscillations.  Although dystonia is less common than Parkinson’s disease, traumatic brain injury, or stroke, each of these common disorders present with dystonia.  Information regarding the brain regions that may be involved in dystonia is surprisingly limited and often conflicting.    With chapters written by subject matter experts, this is a unique title that focuses on dystonia as a network disorder.  This book would be of interest to basic and clinical researchers with an interest in motor systems and movement disorders.


Editors and Affiliations

  • Departments of Neurology and Biomedical Engineering, Case Western Reserve University, Cleveland, USA

    Aasef Shaikh

  • Clinical Lecturer, Movement Disorders and Neuromodulation Group, St George’s University of London, London, UK

    Anna Sadnicka

About the editors

Aasef G Shaikh, MD,PhD is a Penni and Stephen Weinberg Chair in Brain Health at University Hospitals Cleveland. He is a Professor and Vice-Chair for research in Neurology at Case Western Reserve University. Dr Shaikh directs National VA Parkinson Consortium Center at Cleveland VA and is a principal investigator in Daroff DellOsso Oculomotor Laboratory. His interdisciplinary research focuses on motor systems, eye movement and vestibular control. The overarching goal of his research program is to study mechanistic underpinning of complex neurological disorders affecting the eye and head movements and vestibular function.





Dr Anna Sadnicka BSc MBChB MRCP PhD

Anna is a Clinical Lecturer fascinated by the neural control of movement and how this is disturbed in movement disorders.  Her award-winning research combines behavioural experiments, electrophysiology, and computational models to shed light on dystonia mechanism.  She has a particular emphasis on translating her research into novel movement retraining and neuromodulation strategies. 


Bibliographic Information

  • Book Title: Basic and Translational Applications of the Network Theory for Dystonia

  • Editors: Aasef Shaikh, Anna Sadnicka

  • Series Title: Advances in Neurobiology

  • DOI: https://doi.org/10.1007/978-3-031-26220-3

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2023

  • Hardcover ISBN: 978-3-031-26219-7Published: 21 June 2023

  • Softcover ISBN: 978-3-031-26222-7Due: 22 July 2023

  • eBook ISBN: 978-3-031-26220-3Published: 20 June 2023

  • Series ISSN: 2190-5215

  • Series E-ISSN: 2190-5223

  • Edition Number: 1

  • Number of Pages: XI, 242

  • Number of Illustrations: 6 b/w illustrations, 31 illustrations in colour

  • Topics: Neurosciences

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