Overview
- Informs on the biochemistry and cellular biology of aging processes in human cells
- Introduces the historical development and progression in biomedical aging research
- Discusses novel therapeutic opportunities through modulation of cellular senescence
Part of the book series: Subcellular Biochemistry (SCBI, volume 102)
Access this book
Tax calculation will be finalised at checkout
Other ways to access
Table of contents (16 chapters)
-
Front Matter
Keywords
About this book
This book provides a state-of-the-art overview of key areas of subcellular aging research in human cells.
The reader is introduced to the historical development and progress in biomedical aging research and learns, for example, about the role of microRNAs, circRNAs, mitochondria and extracellular vesicles in cellular senescence. The reader will also learn more about how gap junctions, the nuclear pore complex and the proteasome are affecting the ageing processes. In addition, novel therapeutic opportunities through modulation of cellular senescence are discussed.
The book follows on from Parts I and II of Biochemistry and Cell Biology of Ageing (Volumes 90 and 91 of the Subcellular Biochemistry book series) by covering interesting and significant biomedical ageing topics not included in the earlier volumes. Comprehensive and cutting-edge, this book is a valuable resource for experienced researchers and early career scientist alike, who are interested in learning more about the fascinating and challenging question of why and how our cells age.
Editors and Affiliations
About the editors
Prof J. Robin Harris is an Honorary Professor of the University of Mainz, who specialized in macromolecular electron microscopy. He has been the Series Editor of the Subcellular Biochemistry Series for many years and his broad scientific interests are reflected in the diversity of content of the Series.
Dr Viktor Korolchuk is Reader in Molecular Cell Biology at Newcastle University. His scientific interests lie in the area of intracellular protein trafficking and degradation pathways. The current focus of research in his laboratory is autophagy (literally self-eating) where portions of cytoplasm are recruited into intracellular vesicles called autophagosomes and transported for degradation by lysosomal hydrolases.Bibliographic Information
Book Title: Biochemistry and Cell Biology of Ageing: Part III Biomedical Science
Editors: J. Robin Harris, Viktor I. Korolchuk
Series Title: Subcellular Biochemistry
DOI: https://doi.org/10.1007/978-3-031-21410-3
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023
Hardcover ISBN: 978-3-031-21409-7Published: 06 January 2023
Softcover ISBN: 978-3-031-21412-7Published: 07 January 2024
eBook ISBN: 978-3-031-21410-3Published: 04 January 2023
Series ISSN: 0306-0225
Series E-ISSN: 2542-8810
Edition Number: 1
Number of Pages: IX, 424
Number of Illustrations: 1 b/w illustrations
Topics: Aging, Cell Biology, Medical Biochemistry, Protein Science