Overview
- Covers all aspects of DNA-Encoded Library (DEL) technology
- Explores how DEL technology can contribute to hit validation
- Discusses perspectives and challenges on DEL development
Part of the book series: Topics in Medicinal Chemistry (TMC, volume 40)
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Table of contents (8 chapters)
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Front Matter
Keywords
About this book
The book aims to provide a comprehensive overview of all of the major components of the DEL process from conception to bench execution and clinical investigations. The contributions from experts in the field combine different perspectives from academia and industry. The book will be of interest to researchers in the drug discovery field as well as to graduate students and scholars who are interested in this rapidly improving technology.
Editors and Affiliations
About the editors
Damian W. Young received a B.S. degree in chemistry (with ACS Certification) from Howard University. He then spent a year working as a process chemist on the anti-HIV drug Fuzeon at Trimeris Inc. before earning a Ph.D. in organic chemistry from North Carolina State University. Following this, he conducted a postdoctoral fellowship at Harvard University and the Broad Institute of MIT and Harvard. He became a Group Leader within the Chemical Biology Program at the Broad. Dr Young is currently the Associate Director for the Center for Drug Discoveryat Baylor College of Medicine and a faculty member within the Department of Pharmacology and Chemical Biology. His research is focused on the application of diversity-oriented synthesis to DNA encoded chemistry technology and fragment-based drug discovery.
Bibliographic Information
Book Title: DNA-Encoded Libraries
Editors: Andreas Brunschweiger, Damian W. Young
Series Title: Topics in Medicinal Chemistry
DOI: https://doi.org/10.1007/978-3-031-18629-5
Publisher: Springer Cham
eBook Packages: Chemistry and Materials Science, Chemistry and Material Science (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
Hardcover ISBN: 978-3-031-18628-8Published: 26 November 2022
Softcover ISBN: 978-3-031-18631-8Published: 26 November 2023
eBook ISBN: 978-3-031-18629-5Published: 25 November 2022
Series ISSN: 1862-2461
Series E-ISSN: 1862-247X
Edition Number: 1
Number of Pages: IX, 276
Topics: Medicinal Chemistry, Chemistry/Food Science, general, Physical Chemistry, Biological Techniques, Protein Science