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Breath Analysis

An Approach for Smart Diagnostics

  • Book
  • © 2023

Overview

Editors:
  1. Stefan Weigl

    1. Ostbayerische Technische Hochschule Regensburg, Regensburg, Germany

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  • Overview of current status in human breath analysis
  • Presents fundamental research and applications to breath tests
  • Contributions from international experts in the field

Part of the book series: Bioanalytical Reviews (BIOREV, volume 4)

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-xi
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  2. Physio-Metabolic Monitoring via Breath Employing Real-Time Mass Spectrometry: Importance, Challenges, Potentials, and Pitfalls

    • Pritam Sukul, Phillip Trefz
    Pages 1-18

  3. Offline Breath Analysis: Standardization of Breath Sampling and Analysis Using Mass Spectrometry and Innovative Algorithms

    • Rosa A. Sola-Martínez, Gema Lozano-Terol, Julia Gallego-Jara, Manuel Cánovas Díaz, Teresa de Diego Puente
    Pages 19-44

  4. Ion Mobility Spectrometry in Clinical and Emergency Setting: Research and Potential Applications

    • Dorota M. Ruszkiewicz, Austin Meister, Renelle Myers
    Pages 45-71

  5. Infrared Sensing Strategies: Toward Smart Diagnostics for Exhaled Breath Analysis

    • Michael Hlavatsch, Sarah Klingler, Boris Mizaikoff
    Pages 73-100

  6. Scopes and Limits of Photoacoustic Spectroscopy in Modern Breath Analysis

    • Stefan Weigl, Max Müller, Jonas Pangerl, Thomas Rück
    Pages 101-159

  7. Advances of Semiconductor Gas Sensing Materials, Structures, and Algorithms for Breath Analysis

    • Pavel Nosovitskiy, Gennadiy Nosovitskiy, Kiran Nandigam, Ravie Abozaid, Suzanne Karan
    Pages 161-200

  8. Breath Analysis as Part of Pulmonary Function Diagnostics

    • Meike Aufderhaar
    Pages 201-240
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Keywords

About this book

This volume highlights the potentials as well as the limits and challenges of human breath analysis and describes the current efforts made to advance this promising technology from bench to bed. Human breath analysis is a young, interdisciplinary and innovative research field aiming to provide a smart and non-invasive diagnostic tool, which can be used for screening, detecting and monitoring of diseases or metabolic disorders. This book presents different approaches for breath analysis including real-time and offline mass spectrometry as well as optical and semiconductor gas sensing methods. Besides, the role of smart algorithms to improve the performance of those technologies and the importance of pulmonary function diagnostics for more reliable and meaningful breath analysis are highlighted. Finally, current application scenarios and future perspectives of breath analysis and pulmonary functioning tests are addressed.



The volume is useful for researchers, who are new in the field, to easily get an overview of the current status and the challenges present in human breath analysis. Topics from fundamental research over targeted sensor development and application scenarios are described. Thus, this volume covers all development stages providing support and inspiration for engineers, medical doctors and scientists from various fields.

Reviews

“An excellent contribution to breath analysis not only for analytical chemists but also for anybody interested in novel diagnostic approaches and point-of-care testing concepts … . The compilation of chapters is a great inspiration for analytical scientists and researchers … .” (Sabine Szunerits, Analytical and Bioanalytical Chemistry, Vol. 415 (8), 2023)

Editors and Affiliations

  • Ostbayerische Technische Hochschule Regensburg, Regensburg, Germany

    Stefan Weigl

About the editor

Dr. Stefan Weigl received his master’s degree in engineering (M. Eng.) from the Ostbayerische Technische Hochschule (OTH) of Regensburg in Germany in 2016. In the course of his master thesis, he started his research on the photoacoustic gas sensing technique in 2015. He received his Doctorate of Natural Sciences (Dr. rer. nat.) in 2021 at the faculty of chemistry and pharmacy of the University of Regensburg. Within his PhD thesis, he investigated the applicability of UV LEDs and IR lasers for the photoacoustical detection of acetone in human breath exhale. Currently, Dr. Stefan Weigl is part of the photoacoustic team of the Sensorik-Applikationszentrum (SappZ), which is located at the Ostbayerische Technische Hochschule (OTH) of Regensburg and supervises the breath analysis research group.

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