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Acromegaly

A Guide to Diagnosis and Treatment

  • Book
  • © 2022

Overview

Editors:
  1. Lewis S. Blevins Jr.

    1. Department of Neurological Surgery, University of San Francisco, San Francisco, USA

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    You can also search for this editor in PubMed   Google Scholar

  2. Manish K. Aghi

    1. Department of Neurological Surgery, University of San Francisco, San Francisco, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Presents the etiology, diagnosis, management and long-term follow-up for acromegaly
  • Includes chapters on comorbid symptoms as well as medical and surgical treatment
  • An excellent resource for endocrinologists, neuro-endocrinologists and neurosurgeons

Part of the book series: Contemporary Endocrinology (COE)

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Table of contents (21 chapters)

  1. Front Matter

    Pages i-x
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  2. The Molecular Biology and Pathology of Acromegaly

    • Luis R. Carrete, Manish K. Aghi
    Pages 1-14

  3. Growth Hormone-Releasing Hormone-Secreting Neuroendocrine Tumors

    • Thomas M. Fandel, Lewis S. Blevins Jr.
    Pages 15-29

  4. Diagnosis of Acromegaly

    • Nicholas A. Tritos
    Pages 31-41

  5. Imaging in Acromegaly

    • Ian Mark, Javier Villanueva-Meyer
    Pages 43-53

  6. The Clinical Presentation of Acromegaly

    • Lisa B. Nachtigall, Francisco J. Guarda
    Pages 55-65

  7. Sleep-Disordered Breathing in Acromegaly

    • Diane Donegan, Stephanie M. Stahl
    Pages 67-85

  8. Cardiovascular Pathology in Acromegaly

    • Adnan Ajmal
    Pages 87-102

  9. Diabetes Mellitus in Acromegaly

    • Samina Afreen
    Pages 103-110

  10. Musculoskeletal Disorders of Acromegaly

    • Jill B. Feffer
    Pages 111-114

  11. Acromegaly and Cancer

    • Tamis Bright
    Pages 115-148

  12. Mortality in Acromegaly

    • Basma Abdulhadi, Charles Couch Farmer, T. Brooks Vaughan
    Pages 149-160

  13. An Overview of the Approach to the Management of Acromegaly

    • Lewis S. Blevins Jr., Denise Feng, AnneMarie Destruel
    Pages 161-166

  14. Transsphenoidal Surgery for Acromegaly

    • Ryan R. L. Phelps, Jacob S. Young, José Gurrola II, Manish K. Aghi
    Pages 167-184

  15. Stereotactic Radiosurgery and Radiation Therapy for Acromegaly

    • Adomas Bunevicius, Daniel Trifiletti, Jason Sheehan
    Pages 185-206

  16. Challenging Questions in the Management of Acromegaly in the Young

    • Nancy Youssef, Kevin C. J. Yuen
    Pages 207-222

  17. Somatostatin Analogues in the Management of Patients with Acromegaly

    • Lewis S. Blevins Jr.
    Pages 223-225

  18. Use of Dopamine Agonists for Acromegaly

    • Christine E. Chiu, John D. Carmichael
    Pages 227-235

  19. Pegvisomant: Lessons Learned After 20 Years and Practical Recommendations of Its Use for the Treatment of Acromegaly

    • Kevin C. J. Yuen
    Pages 237-252

  20. Perspectives on Combination Medical Therapy in the Treatment of Acromegaly

    • Dawn Shao Ting Lim, Maria Fleseriu
    Pages 253-272
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Keywords

About this book

Reviewing the most current literature, this text is a guide to medical decision-making regarding the diagnosis and treatment of patients with acromegaly. The scope of the book is comprehensive, covering all relevant facets of acromegaly, beginning with a history of the disorder and a review of the somatotrophic axis. Etiology is then discussed, including growth hormone secreting pituitary adenomas and other neuroendocrine tumors. Subsequent chapters present imaging modalities and diagnosis via radiology and clinical findings, as well as comorbid symptoms such as sleep apnea, musculoskeletal considerations, cardiovascular disorders, cancer and diabetes. Both medical and surgical management chapters describe each in detail, including radiotherapy, transsphenoidal surgery, somatostatin analogues and dopamine agonists. Concluding chapters present long-term follow-up as well as an extended selected patient story detailing life with the disease.


Bringing together the latest in endocrinologic and neurosurgical evidence and practice, Acromegaly will be the go-to resource for this challenging condition for years to come. 

Editors and Affiliations

  • Department of Neurological Surgery, University of San Francisco, San Francisco, USA

    Lewis S. Blevins Jr., Manish K. Aghi

About the editors

Lewis S. Blevins Jr., MD, Department of Neurological Surgery, California Center for Pituitary Disorders and Brain Tumor Center, University of California - San Francisco, San Francisco, CA, USA

Manish Aghi, MD, PhD, Department of Neurological Surgery, California Center for Pituitary Disorders and Brain Tumor Center, University of California - San Francisco, San Francisco, CA, USA

Bibliographic Information

  • Book Title: Acromegaly

  • Book Subtitle: A Guide to Diagnosis and Treatment

  • Editors: Lewis S. Blevins Jr., Manish K. Aghi

  • Series Title: Contemporary Endocrinology

  • DOI: https://doi.org/10.1007/978-3-031-16258-9

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-031-16257-2Published: 13 November 2022

  • Softcover ISBN: 978-3-031-16260-2Published: 14 November 2023

  • eBook ISBN: 978-3-031-16258-9Published: 12 November 2022

  • Series ISSN: 2523-3785

  • Series E-ISSN: 2523-3793

  • Edition Number: 1

  • Number of Pages: X, 298

  • Number of Illustrations: 11 b/w illustrations, 10 illustrations in colour

  • Topics: Endocrinology

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