Blood Pressure Disorders in Diabetes Mellitus

1. Front Matter

   Pages i-ix

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2. Introduction

   1. Front Matter

      Pages 1-1

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   2. Coexistence of Diabetes Mellitus and Hypertension

      • Adel E. Berbari, Najla A. Daouk, Edgar M. Nasr

      Pages 3-17

3. Epidemiological Aspects

   1. Front Matter

      Pages 19-19

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   2. Blood Pressure Disorders in Diabetic Children and Adolescents

      • Empar Lurbe

      Pages 21-38

   3. Hypertension and Type 2 Diabetes

      • Josep Redon, Fernando Martinez

      Pages 39-56

   4. Diabetes Complicating Pregnancy and Hypertension

      • Nicholas Baranco, Robert K. Silverman, John T. Nosovitch Jr, Robert Eden, D. S. Mastrogiannis

      Pages 57-70

4. Screening and Diagnostic Approaches in Diabetic Hypertensive Patients

   1. Front Matter

      Pages 71-71

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   2. Office/Out-of-Office Blood Pressure Measurements

      • Paolo Verdecchia, Gianpaolo Reboldi, Fabio Angeli

      Pages 73-88

   3. Laboratory Indices/Bioimaging

      • Maria Lorenza Muiesan, Claudia Agabiti-Rosei, Carolina De Ciuceis, Massimo Salvetti, Anna Paini

      Pages 89-101

5. Pathophysiological Mechanisms

   1. Front Matter

      Pages 103-103

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   2. Molecular Mechanisms Underlying Vascular Disease in Diabetes

      • Rhian M. Touyz, Omotayo Eluwole, Livia L. Camargo, Francisco J. Rios, Rheure Alves-Lopes, Karla B. Neves et al.

      Pages 105-118

   3. Insulin and Blood Pressure Relationships

      • Peter M. Nilsson, Andrea Natali

      Pages 119-128

   4. Mechanisms of Diabetic Nephropathy in Humans and Experimental Animals

      • Charbel C. Khoury, Sheldon Chen, Fuad N. Ziyadeh

      Pages 129-151

   5. Diabetes and Sympathetic Nervous System

      • Gino Seravalle, Guido Grassi

      Pages 153-165

   6. Diabetes and Microcirculation

      • Damiano Rizzoni, Claudia Agabiti-Rosei, Carolina De Ciuceis, Enrico Agabiti Rosei

      Pages 167-177

6. Target Organ Damage in Hypertensive Diabetic Patient

   1. Front Matter

      Pages 179-179

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   2. Endothelial Dysfunction and Large Artery Stiffness

      • Rachel E. D. Climie

      Pages 181-193

   3. The Heart in Diabetic Hypertensive Patients

      • Amera Halabi, Thomas H. Marwick

      Pages 195-215

   4. Cerebrovascular Structural Alterations/Dysautonomic Disorders in Diabetes Mellitus

      • Damiano Rizzoni, Paolo Desenzani

      Pages 217-230

This book provides an in-depth and up-to-date review of the association between blood pressure disorders and diabetes mellitus. In addition, it discusses the specific role of hemodynamic alterations on the vasculature of various target organs (the retina, kidney, brain, and gravid uterus), topics that are infrequently considered and or acknowledged by clinicians.

Covering all aspects of the interaction between metabolic and hemodynamic factors, the book presents
the diverse perspectives of the contributing authors and extensive discussions of issues including diabetic kidney disease, diabetic hypertensive phenotypes and postural hypotension.

• Diabetic hypertensive phenotypes
• Macro / micro angiopathy
• Diabetic kidney disease
• Diabetic retinopathy
• Therapeutic BP / glycemic targets
• Antihypertensive / hypoglycemic agents
• Postural Hypotension

• American University of Beirut Medical Center, Beirut, Lebanon

  Adel E. Berbari

• University of Milano-Bicocca, Milano, Italy

  Giuseppe Mancia

Adel E. Berbari is Emeritus Professor in Faculty of Medicine at the American University of Beirut. He was Professor of Internal Medicine/Physiology at the American University of Beirut Medical Center, Beirut, Lebanon. He graduated in 1959, had his residency training in Medicine at the American University of Beirut Medical Center from 1959 to 1963, and then was Research Fellow at the Peter Bent Brigham Hospital (Hypertension Unit), Boston, USA, from 1963 to 1966. He acted as Research Associate at Peter Bent Brigham Hospital in 1966. He also acted at the American University of Beirut Medical Center as Chairperson of Department of Physiology (1968) and Internal Medicine (1999-2000), and as Head of the division of Nephrology-Hypertension (1977-2001). He was President of the Lebanese Society of Nephrology and Hypertension, Secretary General of the Lebanese Association for the Advancement of Science, Board member of the Lebanese National Council for Scientific Research, and director of the Board of World Hypertension League. He is President of the Lebanese Hypertension League and Director of the Excellence Center of Nephrology-Hypertension division at AUBMC.  He is Board Certified by the European Society of Hypertension as Clinical Hypertension Specialist. His main research interests focus on Hypertension, vascular medicine, and nephrology. 


Giuseppe Mancia is a Professor Emeritus at the University of Milano-Bicocca and served as Professor of Medicine and Head of the First Division of Medicine at San Gerardo Hospital, Monza, Italy. One of the most cited Italian scientists, he is an executive officer of the European Society of Hypertension and Chair of the ESH Educational Committee. Prof. Mancia has served as President of the European Society of Clinical Investigation, of the Italian Society of Hypertension and of the European Society of Hypertension, the International Society of Hypertension, and is a member ‘ex officio’ of the Executive Scientific Council of the American Society of Hypertension, among others. Dr. Mancia’s research interests include pathophysiology, diagnosis and therapy of hypertension, heart failure, coronary and other cardiovascular diseases. His expertise includes ambulatory blood pressure monitoring, neural control of circulation, large artery mechanics, and clinical trials.

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