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Cancer Stem Cell Markers and Related Network Pathways

  • Book
  • © 2022

Overview

Editors:
  1. Shihori Tanabe

    1. National Institute of Health Sciences, Kanagawa, Japan

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  • Written by global experts in the field
  • Contains interesting targets for anti-cancer therapy
  • Reveals new mechanisms of Cancer Stem Cells

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1393)

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Table of contents (7 chapters)

  1. Front Matter

    Pages i-xiv
    Download chapter PDF

  2. Epithelial–Mesenchymal Transition and Cancer Stem Cells

    • Shihori Tanabe
    Pages 1-49

  3. The Transcription Factors Zeb1 and Snail Induce Cell Malignancy and Cancer Stem Cell Phenotype in Prostate Cells, Increasing Androgen Synthesis Capacity and Therapy Resistance

    • Fernanda López-Moncada, Enrique A. Castellón, Héctor R. Contreras
    Pages 51-64

  4. ERBB Signaling Pathway in Cancer Stem Cells

    • Ghmkin Hassan, Masaharu Seno
    Pages 65-81

  5. Functional and Molecular Characters of Cancer Stem Cells Through Development to Establishment

    • Said M. Afify, Ghmkin Hassan, Hiroko Ishii, Sadia Monzur, Hend M. Nawara, Amira Osman et al.
    Pages 83-101

  6. Microenvironment of Cancer Stem Cells

    • Shihori Tanabe
    Pages 103-124

  7. Cancer Stem Cells Contribute to Drug Resistance in Multiple Different Ways

    • Maram H. Zahra, Hend M. Nawara, Ghmkin Hassan, Said M. Afify, Akimasa Seno, Masaharu Seno
    Pages 125-139

  8. Abnormal Glycosylation in Cancer Cells and Cancer Stem Cells as a Therapeutic Target

    • Sabina Quader, Shihori Tanabe, Horacio Cabral
    Pages 141-156
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Keywords

About this book

This book entitled “Cancer Stem Cell Markers and Related Network Path-ways” is about cancer stem cell (CSC) markers and the molecular network pathways. CSCs play an important role in the cancer drug resistance, metastasis and recurrence. Epithelial-mesenchymal transition (EMT) is closely related to CSC phenotype.


This book covers various aspects of the molecular networks related to CSCs including the important phenotypic change such as EMT. Readers will discover the importance of the identification of CSC markers and EMT-related molecules in CSC network pathways.


The CSC signaling pathways and EMT molecular network pathways attract researchers in the field to define the cancer therapeutic targets. Cancer environment is important in the acquisition of CSC phenotype in cells. The revealing of this CSC mystery is across 7 chapters.   


The topic of this book is particularly relevant to research in thefield of cancer and stem cells, as well as the network pathways. We hope that this book helps the readers to be interested in understanding why the CSC concept is important and attractive.

Editors and Affiliations

  • National Institute of Health Sciences, Kanagawa, Japan

    Shihori Tanabe

About the editor

Shihori Tanabe, Ph.D. has been working as a Senior Researcher at the Division of Risk Assessment, Center for Biological Safety and Research, National Institute of Health Sciences from April 2016. From Apr 2005 until Jan 2006 she held a position of a Post Doctoral Fellow at the Laboratory of Cell Signaling, Graduate School of Pharmaceutical Sciences, The University of Tokyo. From Feb 2006 until Mar 2010 she worked as a Researcher at the Division of Cellular and Gene Therapy Products, National Institute of Health Sciences, Tokyo Japan. She also had a position of a Senior Researcher at the Division of Safety Information on Drug, Food and Chemicals, National Institute of Health Sciences (Apr 2010 - Mar 2016, Tokyo Japan)

Bibliographic Information

  • Book Title: Cancer Stem Cell Markers and Related Network Pathways

  • Editors: Shihori Tanabe

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-031-12974-2

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-031-12973-5Published: 03 January 2023

  • Softcover ISBN: 978-3-031-12976-6Published: 04 January 2024

  • eBook ISBN: 978-3-031-12974-2Published: 01 January 2023

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XIV, 156

  • Number of Illustrations: 2 b/w illustrations, 21 illustrations in colour

  • Topics: Cancer Research, Molecular Medicine, Cytogenetics, Drug Resistance

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