Overview
- Provides a complete and updated state-of-art review
- Written by experts in the field
- Addresses the future perspectives in the cardio-immunology field
Part of the book series: Current Clinical Pathology (CCPATH)
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About this book
The development of immunotherapy in oncology field has revolutionized the prognosis of many types of cancer. The immune checkpoint inhibitors target receptors whose inhibition increases the activity of immune system cells against tumor cells. In recent years, new immunotherapies have been studied and approved in a growing number of tumors including melanoma, non-small cell lung cancer (NSCLC), and renal cell cancer (RCC). This volume provides a complete and updated state-of-art review regarding the management of cardiovascular toxicities from new immunotherapies. The manuscript is divided into different sections starting from the relationship between cancer and immune system to let the reader understand the new molecular concepts under immunotherapy development. Subsequent chapters describe specifically the immunotherapy options in solid tumor treatment and the main features of the immuno-related cardiovascular complications. This volume is written by experts in the oncological and cardiovascular fields and aims to provide to clinicians who approach current cancer patients a useful tool to move through the paths of modern cardio-oncology. An important section would afford the most relevant interventions needed to manage the cardiac events, suggesting how to reduce their impact and effects on oncological outcomes. The text concludes by addressing future perspectives in the cardio-immunology field, discussing many aspects such as the early detection of cardiovascular damage and the potential role of liquid biopsy in new damage-related biomarkers discovery.
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Keywords
Table of contents (10 chapters)
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Front Matter
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Back Matter
Editors and Affiliations
About the editors
Antonio Russo, MD
Department of Oncology - A.O.U.P. "P. Giaccone" University Hospital.
Via del Vespro 129, CAP 90127 Palermo, Italy.
Email: antonio.russo@usa.net
Nicola Maurea, MD
Division of Cardiology, Istituto Nazionale Tumori⁻IRCCS-Fondazione G.Pascale
Via Mariano Semmola, 52 80131 Napoli, Italy.
Email: nicolamaurea@virgilio.it
Dimitrios Farmakis, MD, PhD, FESC, FHFA
Assoc. Professor, University of Cyprus Medical School
Shacolas Educational Centre for Clinical Medicine, 215 Palaios dromos Lefkosias Lemesou, 2029, Nicosia, Cyprus
Visiting Professor, National and Kapodistrian University of Athens Medical School
Athens University Hospital Attikon, 1 Rimini St, 12462, Athens, Greece
Email: farmakis.dimitrios@ucy.ac.cy; dimitrios_farmakis@yahoo.com
Antonio Giordano, MD
Sbarro Institute for Cancer Research and Molecular Medicine and Center of Biotechnology
College of Science and Technology, Temple University
200 Tuttleman Learning Center 1809 N 13th Street
Philadelphia, 19122 USA.
Email: giordano@temple.eduBibliographic Information
Book Title: Cardio-Oncology
Book Subtitle: Management of Toxicities in the Era of Immunotherapy
Editors: Antonio Russo, Nicola Maurea, Dimitrios Farmakis, Antonio Giordano
Series Title: Current Clinical Pathology
DOI: https://doi.org/10.1007/978-3-030-97744-3
Publisher: Humana Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
Hardcover ISBN: 978-3-030-97743-6Published: 10 August 2022
Softcover ISBN: 978-3-030-97746-7Published: 10 August 2023
eBook ISBN: 978-3-030-97744-3Published: 09 August 2022
Series ISSN: 2197-781X
Series E-ISSN: 2197-7828
Edition Number: 1
Number of Pages: XIV, 122
Number of Illustrations: 3 b/w illustrations, 18 illustrations in colour
Topics: Oncology, Cardiology, Pathology, Internal Medicine