Advances in Bioinformatics and Computational Biology

1. Front Matter

   Pages i-xii

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2. Applied Bioinformatics and Computational Biology

   1. Front Matter

      Pages 1-1

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   2. Comparative Transcriptome Profiling of Maytenus ilicifolia Root and Leaf

      • Mariana Marchi Santoni, João Vítor Félix de Lima, Keylla Utherdyany Bicalho, Tatiana Maria de Souza Moreira, Sandro Roberto Valentini, Maysa Furlan et al.

      Pages 3-14

   3. Hypusine Plays a Role in the Translation of Short mRNAs and Mediates the Polyamine and Autophagy Pathways in Saccharomyces Cerevisiae

      • Ana Carolina Silva Paiva, Fernanda Manaia Demarqui, Mariana Marchi Santoni, Sandro Roberto Valentini, Cleslei Fernando Zanelli

      Pages 15-25

   4. Topological Characterization of Cancer Driver Genes Using Reactome Super Pathways Networks

      • Rodrigo Henrique Ramos, Jorge Francisco Cutigi, Cynthia de Oliveira Lage Ferreira, Adenilso Simao

      Pages 26-37

3. Bioinformatics and Computational Biology

   1. Front Matter

      Pages 39-39

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   2. CellHeap: A Workflow for Optimizing COVID-19 Single-Cell RNA-Seq Data Processing in the Santos Dumont Supercomputer

      • Vanessa S. Silva, Maiana O. C. Costa, Maria Clicia S. Castro, Helena S. Silva, Maria Emilia M. T. Walter, Alba C. M. A. Melo et al.

      Pages 41-52

   3. Combining Orthology and Xenology Data in a Common Phylogenetic Tree

      • Marc Hellmuth, Mira Michel, Nikolai N. Nøjgaard, David Schaller, Peter F. Stadler

      Pages 53-64

   4. ContFree-NGS: Removing Reads from Contaminating Organisms in Next Generation Sequencing Data

      • Felipe Vaz Peres, Diego Mauricio Riaño-Pachón

      Pages 65-68

   5. Deep Learning-Based COVID-19 Diagnostics of Low-Quality CT Images

      • Daniel Ferber, Felipe Vieira, João Dalben, Mariana Ferraz, Nicholas Sato, Gabriel Oliveira et al.

      Pages 69-80

   6. Feature Importance Analysis of Non-coding DNA/RNA Sequences Based on Machine Learning Approaches

      • Breno Lívio Silva de Almeida, Alvaro Pedroso Queiroz, Anderson Paulo Avila Santos, Robson Parmezan Bonidia, Ulisses Nunes da Rocha, Danilo Sipoli Sanches et al.

      Pages 81-92

   7. Heuristics for Cycle Packing of Adjacency Graphs for Genomes with Repeated Genes

      • Gabriel Siqueira, Andre Rodrigues Oliveira, Alexsandro Oliveira Alexandrino, Zanoni Dias

      Pages 93-105

   8. PIMBA: A PIpeline for MetaBarcoding Analysis

      • Renato R. M. Oliveira, Raíssa Silva, Gisele L. Nunes, Guilherme Oliveira

      Pages 106-116

4. Short Papers

   1. Front Matter

      Pages 117-117

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   2. CEvADA: Co-Evolution Analysis Data Archive

      • Neli José da Fonseca Júnior, Marcelo Querino Lima Afonso, Lucas Bleicher

      Pages 119-124

   3. FluxPRT: An Adaptable and Extensible Proteomics LIMS

      • Elizabeth Regina Alfaro-Espinoza, Lucas Ferreira Paiva, Alessandra C. Faria-Campos, Maria Cristina Baracat-Pereira, Sérgio Vale Aguiar Campos

      Pages 125-130

   4. MathPIP: Classification of Proinflammatory Peptides Using Mathematical Descriptors

      • João Pedro Uchôa Cavalcante, Anderson Cardoso Gonçalves, Robson Parmezan Bonidia, Danilo Sipoli Sanches, André Carlos Ponce de Leon Ferreira de Carvalho

      Pages 131-136

   5. Metagenomic Insights of the Microbial Community from a Polluted River in Brazil 2020

      • Carolina O. P. Gil, Larissa Macedo Pinto, Flavio F. Nobre, Cristiane Thompson, Fabiano Thompson, Diogo Antonio Tschoke

      Pages 137-144

   6. Mesoscopic Evaluation of DNA Mismatches in PCR Primer-Target Hybridisation to Detect SARS-CoV-2 Variants of Concern

      • Pâmella Miranda, Vivianne Basílio Barbosa, Gerald Weber

      Pages 145-150

5. Back Matter

   Pages 151-151

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This book constitutes the refereed proceedings of the Brazilian Symposium on Bioinformatics, BSB 2021, held in November 2021. Due to COVID-19 pandemic the conference was held virtually
The 10 revised full papers and 5 short papers were carefully reviewed and selected from 28 submissions. The papers address a broad range of current topics in computational biology and bioinformatics.

• artificial intelligence
• bioinformatics
• computer networks
• computer science
• computer systems
• computer vision
• data communication systems
• databases
• distributed computer systems
• engineering
• image analysis
• image processing
• image segmentation
• internet
• machine learning
• mathematics
• network protocols
• signal processing
• telecommunication networks
• telecommunication systems

• Leipzig University, Leipzig, Germany

  Peter F. Stadler

• University of Brasília, Brasilia, Brazil

  Maria Emilia M. T. Walter

• CINVESTAV, Irapuato, Mexico

  Maribel Hernandez-Rosales

• Universidade de Brasilia, Brasilia, Brazil

  Marcelo M. Brigido

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