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Healthy Longevity and Immune System

  • Book
  • © 2022

Overview

Editors:
  1. Valquiria Bueno

    1. Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo (UNIFESP), São Paulo, Brazil

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    You can also search for this editor in PubMed   Google Scholar

  2. Graham Pawelec

    1. Department of Immunology, University of Tübingen, Tübingen, Germany

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    You can also search for this editor in PubMed   Google Scholar

  • Discusses changes in the immune system and the possible role played in the morbidities/mortality occurring during aging
  • Describes therapies for aging individuals focusing in Infections (COVID-19), Vaccines, Cancer, and Neurodegeneration
  • Offers future perspectives in interventions and medicaments to alleviate immunosenescence and possible impacts

Part of the book series: Healthy Ageing and Longevity (HAL, volume 16)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Healthy Longevity and Immune System: A Brief Introduction

    • Alphonse Laya, Valquiria Bueno
    Pages 1-12

  3. Age-Related Changes in Primary and Secondary Lymphoid Organs

    • Valquiria Bueno
    Pages 13-22

  4. Immunesenescence and Compromised Removal of Senescent Cells: Implications for Health in Old Age

    • Jon Hazeldine, Janet M. Lord
    Pages 23-52

  5. Myeloid-Derived Suppressive Cells in Ageing and Age-Related Diseases

    • Valquiria Bueno, Graham Pawelec
    Pages 53-64

  6. Effects of Aging and Associated Conditions on Humoral Responses to Respiratory Tract Infections

    • Daniela Frasca
    Pages 65-90

  7. Ageing Mucosal Immunity and Its Consequences for Infectious Diseases in the Aged; A First Glance

    • Marieke van der Heiden, Debbie van Baarle
    Pages 91-117

  8. Vaccines and Vaccination Strategies for Older Adults

    • Birgit Weinberger
    Pages 119-164

  9. Immunosenescence and Cancer

    • Gisele W. B. Colleoni, Valquiria Bueno
    Pages 165-176

  10. Immunosenescence and Alzheimer’s Disease

    • T. Fulop, A. Larbi, A. Khalil, A. Plotka, B. Laurent, C. Ramassamy et al.
    Pages 177-199
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Keywords

About this book

This book presents studies of the main conditions that affect health and well-being of old people. Considering the present scenario of COVID-19, the effects of this viral infection on individuals older than 65 years are also discussed. The content enables professionals of health and government for the present and future actions in this important area.

Readers go through  the changes occurring in organs and tissues that can interfere with susceptibility to infections, low response to vaccines, cancer, and loss of cognition during the aging process.

A discussion of the central role played by the immune system in the age-related diseases and how the immunity can be impaired during the ageing process is presented. Possibilities to circumvent these conditions via healthy habits in diet, physical exercise, and new pharmacological interventions are part of the content.   

This book discusses how human healthy longevity is dependent, at least inpart, of a functional immune system. Chapters were written for researchers in the field of aging and is especially suited for those interested in the study of immunosenescence and inflammaging affecting the health of old individuals.


Editors and Affiliations

  • Department of Microbiology, Immunology and Parasitology, Federal University of São Paulo (UNIFESP), São Paulo, Brazil

    Valquiria Bueno

  • Department of Immunology, University of Tübingen, Tübingen, Germany

    Graham Pawelec

Bibliographic Information

  • Book Title: Healthy Longevity and Immune System

  • Editors: Valquiria Bueno, Graham Pawelec

  • Series Title: Healthy Ageing and Longevity

  • DOI: https://doi.org/10.1007/978-3-030-87532-9

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-030-87531-2Published: 11 November 2021

  • Softcover ISBN: 978-3-030-87534-3Published: 12 November 2022

  • eBook ISBN: 978-3-030-87532-9Published: 10 November 2021

  • Series ISSN: 2199-9007

  • Series E-ISSN: 2199-9015

  • Edition Number: 1

  • Number of Pages: X, 199

  • Number of Illustrations: 4 b/w illustrations, 6 illustrations in colour

  • Topics: Immunology, Aging, Neurosciences, Nutrition, Medicine/Public Health, general

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