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Parkinsonism and the Environment

  • Book
  • © 2022

Overview

Editors:
  1. Nikolay M. Filipov

    1. Department of Physiology and Pharmacology, College of Veterinary Medicine, Interdisciplinary Toxicology Program University of Georgia, Athens, USA

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  • No such book currently exist
  • The interest in the role the environment plays in neurodegeneration is immense and continues to rise
  • Compiling chapters from the true experts in the field in a single, focused book, is unique for the field

Part of the book series: Molecular and Integrative Toxicology (MOLECUL)

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Table of contents (6 chapters)

  1. Front Matter

    Pages i-v
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  2. The Use and Predictability of C. elegans as an Alternative and Complementary Model in Neurotoxicological Studies: Focus on the Dopaminergic System

    • Marina Lopes Machado, Daniele Coradini Zamberlan, Leticia Priscilla Arantes, Michael Aschner, Félix Antunes Soares
    Pages 1-18

  3. Emerging Contaminants as Contributors to Parkinsonism: Heterocyclic Amines

    • Rachel Foguth, Jason Cannon
    Pages 19-37

  4. Aberrant Dopamine Homeostasis as a Focal Point in the Mechanism of Environmental Contaminant-Induced Dopaminergic Dysfunction

    • Brianna S. Cagle, Rachel A. Crawford, Jonathan A. Doorn
    Pages 39-68

  5. The Environmental Contribution to Redox Dyshomeostasis in Parkinson’s Disease

    • Carla Garza-Lombó, Rodrigo Franco
    Pages 69-102

  6. PKC-Delta Is a Major Molecular Target for Diverse Dopaminergic Toxicants: Implications for Mechanistic and Translational Neurotoxicology

    • Zainab Riaz, Adhithiya Charli, Hannah Wickham, Huajun Jin, Gary Zenitsky, Vellareddy Anantharam et al.
    Pages 103-129

  7. Pesticides Exposures and Parkinsonism: Experimental and Epidemiological Evidence of Association

    • Nikolay M. Filipov
    Pages 131-154

  8. Back Matter

    Pages 155-158
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Keywords

About this book

“The book is comprised of individual reviews with the common goal of providing up-to-date state of the knowledge information on the role the environment plays in the pathogenesis of parkinsonism. The reviews focus on recent advances in the quest of deciphering the molecular and cellular mechanisms of parkinsonian dysfunction, highlight specific emerging dopaminergic toxicants and an alternative experimental model to study the link between environmental exposures and parkinsonism, and provide an update from epidemiological and experimental points of view related to the pesticide exposures and parkinsonism/Parkinson’s Disease association. Foremost experts in their respective fields are the senior authors on each chapter and the book fills a critical void that now exists as a book of similar nature has not been published in the last 15 years. Researchers and clinicians with an interest in Parkinson's Disease and related disorders, as well as toxicologists, graduate students, and the general public who are interested in the contribution of environmental factors to neurological dysfunction are among the readership for this book.”

Editors and Affiliations

  • Department of Physiology and Pharmacology, College of Veterinary Medicine, Interdisciplinary Toxicology Program University of Georgia, Athens, USA

    Nikolay M. Filipov

About the editor

Dr. Filipov is a Professor in the Department of Physiology and Pharmacology of the University of Georgia. He is also part of the university’s Interdisciplinary Toxicology and Neuroscience programs. His research is focused in large part on the role certain pesticides and metals play in the pathogenesis of basal ganglia disorders of parkinsonian nature

Bibliographic Information

  • Book Title: Parkinsonism and the Environment

  • Editors: Nikolay M. Filipov

  • Series Title: Molecular and Integrative Toxicology

  • DOI: https://doi.org/10.1007/978-3-030-87451-3

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022

  • Hardcover ISBN: 978-3-030-87450-6Published: 20 February 2022

  • Softcover ISBN: 978-3-030-87453-7Published: 21 February 2023

  • eBook ISBN: 978-3-030-87451-3Published: 18 February 2022

  • Series ISSN: 2168-4219

  • Series E-ISSN: 2168-4235

  • Edition Number: 1

  • Number of Pages: V, 158

  • Number of Illustrations: 6 b/w illustrations, 8 illustrations in colour

  • Topics: Pharmacology/Toxicology, Neurosciences

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