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Practical Oncologic Molecular Pathology

Frequently Asked Questions

  • Book
  • © 2021

Overview

Editors:
  1. Yi Ding

    1. Department of Laboratory Medicine, Geisinger Health, Danville, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Linsheng Zhang

    1. Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Emphasizes the interpretation of molecular tests in the context of clinical management
  • Provides clear descriptions and illustrations for each topic
  • Written by experts actively practicing in each field

Part of the book series: Practical Anatomic Pathology (PAP)

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Table of contents (20 chapters)

  1. Front Matter

    Pages i-xii
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  2. Molecular Methods and Data Analysis in Clinical Molecular Diagnostic Laboratories

    1. Front Matter

      Pages 1-1
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    2. The Molecular Pathobiology of Malignant Process and Molecular Diagnostic Testing for Cancer

      • Yi Ding, Linsheng Zhang
      Pages 3-21

    3. Molecular Diagnostic Methods

      • Terrance J. Lynn, Andrew Campbell
      Pages 23-54

    4. Bioinformatics Analysis in Molecular Pathology

      • Geoffrey H. Smith
      Pages 55-76

    5. Quality Assurance and Quality Control in Molecular Diagnostic Laboratories

      • Juehua Gao, Lawrence J. Jennings
      Pages 77-85

  3. Molecular Pathology of Solid and Soft Tissue Tumors

    1. Front Matter

      Pages 87-87
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    2. Breast and Gynecologic Tumors

      • Huina Zhang, David G. Hicks
      Pages 89-120

    3. Tumors of the Central Nervous System

      • José E. Velázquez Vega, Leomar Y. Ballester, Matthew J. Schniederjan
      Pages 121-145

    4. Lung Cancer

      • Ruifang Zheng, Linsheng Zhang
      Pages 147-169

    5. Gastrointestinal, Hepatobiliary, and Pancreatic Tumors

      • Mohammad K. Mohammad, Guoli Chen
      Pages 171-187

    6. Skin Tumors

      • Cynthia Reyes Barron, Bruce R. Smoller
      Pages 189-206

    7. Soft Tissue Tumors

      • Anthony P. Martinez
      Pages 207-231

    8. Genitourinary Neoplasms

      • Yi Ding, Khaleel I. Al-Obaidy, Liang Cheng
      Pages 233-244

    9. Hereditary Cancer Syndromes and Inherited Cancer Risks

      • Kristin K. Deeb, Mariana Kekis, Tatiana Tvrdik
      Pages 245-271

  4. Molecular Hematopathology

    1. Front Matter

      Pages 273-273
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    2. Acute Myeloid Leukemia

      • Guang Yang, Linsheng Zhang
      Pages 275-304

    3. Myeloproliferative Neoplasms, Myelodysplastic/Myeloproliferative Neoplasms, and Myelodysplastic Syndromes

      • Julie Li, Gang Zheng
      Pages 305-323

    4. Precursor Lymphoid Neoplasms

      • Xiaohui Zhang
      Pages 325-338

    5. Mature B-Cell Neoplasms

      • Yi Ding
      Pages 339-359
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Keywords

About this book

This book is a review and high-yield reference on the clinical molecular diagnostics of malignant neoplasms. It aims to address the practical questions frequently encountered in the molecular oncology practice, as well as key points and pitfalls in the clinical interpretation of molecular tests in guiding precision cancer management. The text uses a Q&A format and case presentations, with emphasis on understanding the molecular test methods, diagnosis, classification, risk assessment and clinical correlation. Starting with an update on the molecular biology of cancer, the book focuses on the topics related to molecular diagnostics and genetics-based precision oncology. Separate chapters are dedicated to discussion of the bioinformatics for the analysis of genetic/genomic data generated from molecular assays, and quality control (QC)/quality assurance (QA) programs in the clinical laboratories; both are critical in producing high quality results for clinical care of cancer patients. These are followed by organ system-based reviews and discussions on the molecular genetic abnormalities and related tests covering diverse types of common to rare malignant neoplasms. This book also provides up-to-date knowledge related to malignant neoplasms, discusses the established as well as evolving requirements for pathologic diagnosis of these malignancies. It also discusses the cost effective utilization of molecular tests in clinical oncology.


Written by experts in the field, Practical Oncologic Molecular Pathology serves as a valuable reference for practicing pathologists, fellows, residents and other health care professionals. 

Editors and Affiliations

  • Department of Laboratory Medicine, Geisinger Health, Danville, USA

    Yi Ding

  • Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, USA

    Linsheng Zhang

About the editors

Yi Ding MD, PhD
Department of Laboratory Medicine, Diagnostic Medicine Institute
Geisinger Health
Danville, PA
USA


Linsheng Zhang MD, PhD
Department of Pathology and Laboratory Medicine
Emory University School of Medicine
Atlanta, GA
USA



Bibliographic Information

  • Book Title: Practical Oncologic Molecular Pathology

  • Book Subtitle: Frequently Asked Questions

  • Editors: Yi Ding, Linsheng Zhang

  • Series Title: Practical Anatomic Pathology

  • DOI: https://doi.org/10.1007/978-3-030-73227-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021

  • Hardcover ISBN: 978-3-030-73226-4Published: 12 July 2021

  • Softcover ISBN: 978-3-030-73229-5Published: 13 July 2022

  • eBook ISBN: 978-3-030-73227-1Published: 10 July 2021

  • Series ISSN: 2629-3692

  • Series E-ISSN: 2629-3706

  • Edition Number: 1

  • Number of Pages: XII, 449

  • Number of Illustrations: 11 b/w illustrations, 181 illustrations in colour

  • Topics: Pathology, Oncology

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