Overview
- Unique East-meets-West perspectives on asthma treatments;
- Mechanistic analysis of asthma pathophysiology;
- Alternative approaches and philosophies to asthma management with plant-based therapy.
Part of the book series: SpringerBriefs in Immunology (BRIEFSIMMUN)
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About this book
Asthma is a chronic airway disease affecting over 300 million people worldwide with an expected increase of an additional 100 million by 2025. Past decade has observed a notable increase in asthma prevalence on both national and global levels with highest rates observed in western countries (about 30%). Over the past 40 years, a drastic increase in global prevalence, morbidity, mortality, and economic burden have been observed due to asthma especially in children. The rising numbers of hospital admissions for asthma, especially young children, reflect an increase in severe asthma, poverty and lack of proper disease management. Worldwide, approximately 180,000 deaths annually are caused due to this condition. The financial burden on a single asthma patient per year in different western countries ranges from US$300–1,300.
Asthma is an intricate respiratory disorder with differences in its severity, natural history and hence treatment response. These differences in intensities of various presentations such as bronchial hyper-responsiveness, airway inflammation, mucus production, airflow obstruction make asthma a heterogeneous disease. The mainstay of current therapies for asthma includes inhaled corticosteroids, phosphodiesterase inhibitors, leukotriene modifiers and β2-adrenoceptor agonists. Some of the currently available drugs are efficient in one or more aspects. However the associated side effects or heterogeneity of the disease limit their usefulness and efficacy, thereby putting a demand on development of new drugs and therapies. On the other hand, asthma has also been treated/managed via herbal medications. These approaches have been described in Unani, Ayurvedic or Chinese system of medicine since antiquity. In fact, several anti-asthmatic drugs were developed from herbs commonly utilized in the non-Western system of medicine.
This book focuses on the pathophysiology of asthma, its medication (both herbaland modern), limitations and their future prospects.
Asthma is an intricate respiratory disorder with differences in its severity, natural history and hence treatment response. These differences in intensities of various presentations such as bronchial hyper-responsiveness, airway inflammation, mucus production, airflow obstruction make asthma a heterogeneous disease. The mainstay of current therapies for asthma includes inhaled corticosteroids, phosphodiesterase inhibitors, leukotriene modifiers and β2-adrenoceptor agonists. Some of the currently available drugs are efficient in one or more aspects. However the associated side effects or heterogeneity of the disease limit their usefulness and efficacy, thereby putting a demand on development of new drugs and therapies. On the other hand, asthma has also been treated/managed via herbal medications. These approaches have been described in Unani, Ayurvedic or Chinese system of medicine since antiquity. In fact, several anti-asthmatic drugs were developed from herbs commonly utilized in the non-Western system of medicine.
This book focuses on the pathophysiology of asthma, its medication (both herbaland modern), limitations and their future prospects.
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Keywords
Table of contents (14 chapters)
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Front Matter
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Back Matter
Authors and Affiliations
About the authors
Dr Rayees Sheikh is a postdoctoral research associate at the University of Illinois at Chicago. His research focuses on the inflammation signaling mechanisms of lung diseases. He was recently awarded prestigious Ramalingaswami Fellowship by Department of Biotechnology, Government of India. He has published extensively in international peer-reviewed journals as well as contributed book chapters on plant-based therapeutics for human disorders.
Dr Inshah Din is a research scholar at Government Medical College at Srinagar, India. She also worked as a Junior Reseach Fellow at the prestigious Sher-i-Kashmir Institute of Medical Sciences, and has published primary research articles and book chapters with international publishing houses. Her clinical research evaluates the possible connection between diabetes development via the adipokine and vitamin D axis. Her other work studies the efficacy of herbal medicine on chronic human conditions.
Dr Inshah Din is a research scholar at Government Medical College at Srinagar, India. She also worked as a Junior Reseach Fellow at the prestigious Sher-i-Kashmir Institute of Medical Sciences, and has published primary research articles and book chapters with international publishing houses. Her clinical research evaluates the possible connection between diabetes development via the adipokine and vitamin D axis. Her other work studies the efficacy of herbal medicine on chronic human conditions.
Bibliographic Information
Book Title: Asthma: Pathophysiology, Herbal and Modern Therapeutic Interventions
Authors: Sheikh Rayees, Inshah Din
Series Title: SpringerBriefs in Immunology
DOI: https://doi.org/10.1007/978-3-030-70270-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Author(s), under exclusive licence to Springer Nature Switzerland AG 2021
Softcover ISBN: 978-3-030-70269-4Published: 27 March 2021
eBook ISBN: 978-3-030-70270-0Published: 26 March 2021
Series ISSN: 2194-2773
Series E-ISSN: 2194-2781
Edition Number: 1
Number of Pages: IX, 69
Number of Illustrations: 1 b/w illustrations, 3 illustrations in colour
Topics: Pneumology/Respiratory System, Plant Biochemistry, Complementary & Alternative Medicine, Physiology, Cardiovascular Biology, Immunology