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Chemotherapy and Pharmacology for Leukemia in Pregnancy

Guidelines and Strategies for Best Practices

  • Fills a critical gap in the oncology/hematology field.

  • Focuses on a special group of oncology patients: pregnant women with leukemia.

  • Details the many unique aspects of treatment for leukemia’s complex set of diseases.

  • Gathers important and practical information in an easy-to-read format.

  • Presents a broad range of trials, doses, approaches, and a completely customized treatment approach.

  • Aimed at professionals from a wide range of fields (hospitals, clinics, fellowship and residency programs, pharmaceutical companies, and others).

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Table of contents (11 chapters)

  1. Front Matter

    Pages i-x
  2. Introduction

    • Gustavo Alves
    Pages 1-21
  3. Clinical Perspectives for Leukemia Treatment During Pregnancy

    • Giancarlo Fatobene, Ana Costa Cordeiro, Maria Cecília Borges Bittencourt, Rafael Fernandes Pessoa Mendes
    Pages 23-48
  4. Chemotherapy Protocols for Leukemia During Pregnancy

    • Kaléu Mormino Otoni, Karla Bruna Nogueira Torres Mormino, Ranieri Sales de Souza Santos, Aline Rebeca de Sousa Magalhães
    Pages 49-75
  5. Clinical Care of the Fetus and the Mother: Obstetrics Management for Patients on Treatment for Leukemia

    • Gilmar de Souza Osmundo Junior, Ana Maria Kondo Igai, Rossana Pulcineli Vieira Francisco
    Pages 95-104
  6. Antibiotic and Antifungal Therapies During Leukemia Treatment in Pregnancy

    • Bruno Azevedo Randi, Vinicius Ponzio da Silva
    Pages 105-120
  7. Transfusion in Pregnant Patients Receiving Treatment for Leukemia

    • Mariângela Borges Ribeiro da Silva
    Pages 121-137
  8. Dose Adjustment of Chemotherapy for Leukemia in Pregnancy Based on Serum Dosages

    • Karla Rodrigues Andrade, Danilo Belchior Ponciano
    Pages 139-143
  9. Supportive Drugs in Leukemia Treatment During Pregnancy

    • Celina de Jesus Guimarães, Sarah Sant’ Anna Maranhão, Pedro Mikael da Silva Costa, Claudia Pessoa
    Pages 145-179
  10. Breastfeeding During Chemotherapy Treatment for Leukemia

    • Carolina Witchmichen Penteado Schmidt
    Pages 181-193
  11. Palliative Care for Patients with Leukemia During Pregnancy

    • Andrea Maria Novaes Machado, Polianna Mara Rodrigues de Souza
    Pages 195-201
  12. Back Matter

    Pages 203-210

About this book

In response to the complexity involved in treating leukemia during pregnancy, and the need to find the most efficient treatment possible without harming the fetus, this book offers essential guidelines for institutions and practitioners alike.

Pursuing a comprehensive approach, the book addresses a broad range of subjects, including: pregnancy and its characteristics; staging, pathology, morbidity and what to expect in each type of leukemia; chemotherapy for leukemia in pregnant women with complete trials; dose adjustment of chemotherapy for leukemia in pregnancy based on serum dosages; and pharmacokinetics and pharmacodynamics for this unique group of patients. In turn, subsequent chapters focus on protecting the fetus and neonatal management regarding chemotherapy for leukemia in pregnancy, including the treatment and risks for the fetus (for each type of leukemia), intrathecal therapy and its effects on the fetus; supportive drugs, antibiotics and antifungals for pregnant patients during chemotherapy, including intervention and dose adjustments; palliative care for women with leukemia in pregnancy; breastfeeding during treatment for leukemia; pharmacological aspects of supplements, vitamins and nutrition in pregnancy during leukemia treatment; and more.

Combining contributions from highly qualified hematology professionals, who have pooled their knowledge to address the treatment of virtually every aspect of leukemia in pregnancy, the book is aimed at a complete pharmacological treatment, including guidelines and trials. It is a must-have not only for institutions providing care for hematology patients, but also for residency programs, research institutions, and professionals in areas that involve leukemia treatment for pregnant women — e.g. hematology, neonatology, obstetrics clinics, intensive medicine and critical care units.

Editors and Affiliations

  • Pediatric Oncology Pharmacist & Scientific Writer, Curitiba, Brazil

    Carolina Witchmichen Penteado Schmidt

  • Pronutrir Nutritional Support and Chemotherapy Ltda, Fortaleza, Brazil

    Kaléu Mormino Otoni

About the editors

Carolina Witchmichen Penteado Schmidt

Author of the Springer books “Pediatric Oncologic Pharmacy—A Complete Guide to Practice” (2019), “Chemotherapy in Neonates and Infants—Pharmacological Oncology for Children Under 1 Year Old” (2018) and “Drug Therapy and Interactions in Pediatric Oncology—A Pocket Guide” (2017). Pediatric Oncology Pharmacist with extensive experience in chemotherapy for children. Oncological Hospital Pharmacy specialist with an MBA in Planning and Business Management. Substantial experience at hospitals and clinics, with pharmacy, drug interactions, pediatrics, oncology, hematology, stem cell transplantation, neonatology, intensive health care and infectology. Academic experience in pharmacy, pediatrics, oncology and hematology; teaching for specialists including pharmacists, physicians and nurses. Author of numerous children’s books about cancer, under the pen name Carola Schmidt, such as Chubby’s Tale—The true story of a teddy bear who beat cancer, and Bald is Beautiful—A letter for a fabulous girl.

 

Kaléu Mormino Otoni

Oncology Pharmacist with experience at major centers of excellence for cancer treatment, e.g. the AC Camargo Cancer Center and Nove de Julho Hospital. He was Regional Representative of the Brazilian Society of Pharmacists in Oncology (SOBRAFO) for the State of São Paulo (2018 - 2019). Specialist in Oncology Hospital Pharmacy at AC Camargo Cancer Center and has an MBA in Health Management from the University of São Paulo (USP). Experience in chemotherapy manipulation, clinical oncology pharmacy, pediatric oncology and hematology, adult oncohematology, and oncology at the intensive care unit. He currently works as an Oncologist Pharmacist at Pronutrir clinic in Ceará/Brazil and Professor for graduate courses in Oncology Pharmacy; also offers training for hospital health professionals. Coauthor of the chapter Drug Interactions in Oncohematology and SCT (Interações Medicamentosas em Onco-Hematologia e TMO) in the book “Hospital Gastronomy in Cancer and BMT” (Gastronomia Hospitalar no Câncer e TMO, Celso Massumoto); and Peer Reviewer for oncology publications.

Bibliographic Information

  • Book Title: Chemotherapy and Pharmacology for Leukemia in Pregnancy

  • Book Subtitle: Guidelines and Strategies for Best Practices

  • Editors: Carolina Witchmichen Penteado Schmidt, Kaléu Mormino Otoni

  • DOI: https://doi.org/10.1007/978-3-030-54058-6

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2021

  • Softcover ISBN: 978-3-030-54057-9Published: 27 September 2020

  • eBook ISBN: 978-3-030-54058-6Published: 26 September 2020

  • Edition Number: 1

  • Number of Pages: X, 210

  • Number of Illustrations: 2 b/w illustrations, 2 illustrations in colour

  • Topics: Hematology, Pharmacotherapy, Obstetrics/Perinatology/Midwifery, Maternal and Child Health

Buy it now

Buying options

eBook USD 39.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access