Genomics, Proteomics, and Metabolomics

1. Front Matter

   Pages i-xv

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2. Trying to Reveal the Mysteries of Stem Cells Using “Omics” Strategies

   • Khadijeh Falahzadeh, Masumeh Jalalvand, Sepideh Alavi-Moghadam, Nikoo Bana, Babak Negahdari

   Pages 1-50

3. Genomics, Proteomics, and Metabolomics for Stem Cells Monitoring in Regenerative Medicine

   • Saeed Heidari-Keshel, Azam Rahimi, Mostafa Rezaei-Tavirani, Farshid Sefat, Arash Khojasteh

   Pages 51-66

4. Metabolic Profiling of the Mesenchymal Stem Cells’ Secretome

   • Kambiz Gilany, Mohammad Javad Masroor, Arash Minai-Tehrani, Ahmad Mani-Varnosfaderani, Babak Arjmand

   Pages 67-81

5. Different Gene Expression Profile of Mesenchymal Stem Cells from Various Sources

   • Babak Arjmand, Negar Ranjbaran, Fatemeh Khatami, Mehrdad Hashemi

   Pages 83-96

6. Genomic and Proteomic Monitoring of Stem Cell-Derived Exosomes

   • Erdal Karaöz, Eda Sun

   Pages 97-106

7. Proteomics Approaches Applied to Regenerative Medicine: Perspectives in Stem Cell Proteomics

   • Saeed Heidari-Keshel, Mostafa Rezaei-Tavirani, Azam Rahimi, Farshid Sefat, Arash Khojasteh

   Pages 107-121

8. Lipidomics of Adipogenic Differentiation of Mesenchymal Stem Cells

   • Kambiz Gilany, Moloud Payab, Parisa Goodarzi, Akram Tayanloo-Beik, Sepideh Alavi-Moghadam, Maryamossadat Mousavi et al.

   Pages 123-140

9. OMICs Profiling of Cancer Cells

   • Bagher Larijani, Parisa Goodarzi, Motahareh Sheikh Hosseini, Solmaz M. Nejad, Sepideh Alavi-Moghadam, Masoumeh Sarvari et al.

   Pages 141-157

10. Genomics, Proteomics, and Metabolomics of Cancer Stem Cells (CSCs)

    • Fatemeh Khatami, Seyed Mohammad Tavangar, Navaz Karimian Pour

    Pages 159-179

11. From OMICs to Ethics: Points to Start the Debate

    • Leila Afshar

    Pages 181-191

12. Back Matter

    Pages 193-199

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This book provides thorough coverage of high-throughput OMICs technologies for the monitoring of stem cells and regenerative medicine. Specific topics covered include the genomics, proteomics, and metabolomics aspects of regenerative medicine, metabolic profiling of mesenchymal stem cells, genome profiling of mesenchymal stem cells, OMICs monitoring of stem cell-derived exosomes, stem cell proteomics, lipidomics, OMICs profiling of cancer (stem) cells, and finally ethical considerations of OMICs-based investigations. Chapters are authored by world-renowned scientists who have valuable expertise in the field of OMICs and regenerative medicine.

Genomics, Proteomics, and Metabolomics: Stem Cells Monitoring in Regenerative Medicine, part of Springer’s Stem Cell Biology and Regenerative Medicine series, is essential reading for researchers, clinicians, biologists, biochemists, and pharmaceutical experts conducting research in the fields of stem cell biology, molecularaspects of stem cell research, tissue engineering, regenerative medicine, cellular therapy, OMICs, bioinformatics, and ethics.

• metabolomics
• proteomics
• sem Cells Monitoring
• endogenous Metabolites
• adipose derived stem cells
• stem cell systems
• OMICs
• transcriptomics

• Cell Therapy and Regenerative Medicine Research Center, Endocrinology and Metabolism, Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Metabolomics and Genomics Research Center, Endocrinology and Metabolism, Molecular-Cellular Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran

  Babak Arjmand

Babak Arjmand, M.D., Ph.D, was graduated from Iran University of Medical Sciences in medicine and received his Ph.D. degree in applied cell science from Tehran University of Medical Sciences, Tehran, Iran. He is currently Head and Director of Stem Cell and Regenerative Medicine Research Center, Endocrinology and Metabolism Cellular-Molecular Sciences Institute, Tehran University of Medical Sciences in Tehran, Iran. His research activities concern the development of cell- and gene-based clinical products through the translational pathway from the basic to the clinic focusing on GLP, GMP, and GCP standards. 

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