Overview
- Superb overview of the relevance of ghrelin to physiology and as a modulator of function.
- Covers all of the molecular and clinical issues, providing basic translational research on ghrelin with results of clinical investigations
- Advances our clinical understanding of obesity, growth, and reproductive pathogenesis
- Authored by leading international investigators in the field
Part of the book series: Contemporary Endocrinology (COE, volume 10)
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About this book
Ghrelin, the endogenous ligand for the growth hormone secretagogue (GHS) receptor, is critical in the control of food intake and energy balance. The ghrelin receptors are now known to have important physiological properties as modulators of growth hormone release, appetite, glucose homeostasis, metabolism, immune function, neurotransmitter activity, cognitive function and neurodegeneration. Bringing all of this information together in the first comprehensive text on the topic, Ghrelin in Health and Disease provides a state-of-the-art synthesis of the latest work in this area for physicians and physician-scientists. This volume addresses the unique property of ghrelin as a modulator of function. Such a property provides potential utility for safe intervention in a wide variety of disease states. Indeed as we learn more about the basic physiology of ghrelin, the potential for treating new disease targets emerge requiring validation in the clinic. Each chapter in this volume is authored by a leading investigator in the field. The introductory chapter sets the background for the book and provides a superb overview of the relevance of ghrelin to physiology, describing how the discovery of ghrelin has prompted us to completely rethink traditional physiology. The authors conclude their chapters by critically addressing the future translational aspects of ghrelin biology and outlining what key basic research and clinical questions remain to be addressed. An invaluable resource, Ghrelin in Health and Disease distinguishes itself as the first comprehensive title covering all of the molecular and clinical issues relating to ghrelin and advancing our clinical understanding of obesity, growth, and reproductive pathogenesis.
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Table of contents (16 chapters)
Editors and Affiliations
Bibliographic Information
Book Title: Ghrelin in Health and Disease
Editors: Roy G. Smith, Michael O. Thorner
Series Title: Contemporary Endocrinology
DOI: https://doi.org/10.1007/978-1-61779-903-7
Publisher: Humana Totowa, NJ
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Science+Business Media New York 2012
Hardcover ISBN: 978-1-61779-902-0Published: 20 October 2012
Softcover ISBN: 978-1-62703-879-9Published: 09 November 2014
eBook ISBN: 978-1-61779-903-7Published: 19 October 2012
Series ISSN: 2523-3785
Series E-ISSN: 2523-3793
Edition Number: 1
Number of Pages: XIV, 290
Topics: Endocrinology, Geriatrics/Gerontology, Immunology, Neurosciences, Nutrition