Overview
- Editors:
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Ali R. Rajabi-Siahboomi
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VP & Chief Scientific Officer, Colorcon Inc., Harleysville, USA
- Comprehensive update on new and emerging approaches in the design of multiparticulate dosage forms
- Covers the opportunities and hidden challenges that arise during formulation
- Scale-up and manufacture Features case studies illustrating best practices
- Includes supplementary material: sn.pub/extras
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Table of contents (14 chapters)
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- Richard Sidwell, Jason Hansell, Manish Rane, Ali R. Rajabi-Siahboomi
Pages 5-35
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- Markus Thommes, Peter Kleinebudde
Pages 37-63
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- David M. Jones, Ali R. Rajabi-Siahboomi
Pages 65-93
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- Marina Levina, Hue Voung, Ali R. Rajabi-Siahboomi
Pages 95-118
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- Sandile M. M. Khamanga, Roderick B. Walker
Pages 119-154
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- W. Brett Caldwell, Aditya M. Kaushal
Pages 155-168
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- Affiong Iyire, Afzal R. Mohammed
Pages 213-236
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- Theresia Kuntz, Wolfgang Weisbrod, Subhashis Chakraborty, Brigitte Skalsky
Pages 237-266
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- Ali R. Rajabi-Siahboomi, Raxit Y. Mehta, Vaibhav Ambudkar, Viena Dias, Sandip Tiwari
Pages 267-299
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- Stefan Dietrich, Dieter Petrak
Pages 301-332
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- Guia Bertuzzi, Stefania Barzanti
Pages 333-357
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Back Matter
Pages 387-396
About this book
Authored by leading experts from academia, users and manufacturers, this book provides an authoritative account of the science and technology involved in multiparticulate drug delivery systems which offer superior clinical and technical advantages over many other specialized approaches in drug delivery. The book will cover market trends, potential benefits and formulation challenges for various types of multiparticulate systems. Drug solubility, dose, chemistry and therapeutic indications as well as excipient suitability coupled with manufacturing methods will be fully covered. Key approaches for taste-masking, delayed release and extended release of multiparticulates systems are of significant interest, especially their in-vivo and in-vitro performance. In addition, the principles of scale-up, QbD, and regulatory aspects of common materials used in this technology will be explained, as well as recent advances in materials and equipment enabling robust, flexible and cost-effective manufacture. Case studies illustrating best practices will also make the book a valuable resource to pharmaceutical scientists in industry and academia.
Editors and Affiliations
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VP & Chief Scientific Officer, Colorcon Inc., Harleysville, USA
Ali R. Rajabi-Siahboomi
About the editor
Ali Rajabi-Siahboomi is Vice President and Chief Scientific Officer at Colorcon Inc. He obtained his PhD in Pharmacy from University of Nottingham (UK). Dr. Rajabi-Siahboomi held various academic positions in Nottingham and Liverpool JM Universities (UK), before joining Colorcon. His main research interests are in the area of solid dosage form pharmaceutics and pharmaceutical technology with emphasis on oral drug delivery systems. He has published over 150 articles, book chapters, abstracts and patents.
