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  • © 2016

Genetics of Melanoma

  • Explores recent discoveries in the field of melanoma genetics
  • Provides practical information for physicians and scientists
  • Features up-to-date chapters written by experts
  • Includes supplementary material: sn.pub/extras

Part of the book series: Cancer Genetics (CANGENETICS)

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xv
  2. Pathogenesis of Melanoma

    1. Front Matter

      Pages 1-1
    2. The Biology of Melanoma

      • Tao Wang, Sook Jung Yun, Xiaowei Xu
      Pages 3-29
    3. The Role of the Immune System and Immunoregulatory Mechanisms Relevant to Melanoma

      • Cara Haymaker, Geok Choo Sim, Marie-Andree Forget, Jie Qing Chen, Chantale Bernatchez, Laszlo Radvanyi
      Pages 31-65
  3. Clinical and Pathological Aspects of Melanoma

    1. Front Matter

      Pages 67-67
    2. Pathology of Melanoma

      • Victor G. Prieto, Christopher R. Shea
      Pages 85-113
  4. Genetics of Melanoma

    1. Front Matter

      Pages 115-115
    2. Inherited Gene Mutations in Melanoma

      • Lana N. Pho, Marjan Champine, Sancy A. Leachman, Wendy Kohlmann
      Pages 117-149
    3. The MAPK Pathway in Melanoma

      • Leomar Y. Ballester, Phyu P. Aung, Chyi-Chia R. Lee
      Pages 151-163
    4. The PI3K-AKT Pathway in Melanoma

      • Alan E. Siroy, Michael A. Davies, Alexander J. Lazar
      Pages 165-180
    5. Biomarker Analysis of Gene-Mutated Protein Products by Immunohistochemistry in Melanoma

      • Carlos A. Torres-Cabala, Michael T. Tetzlaff, Jonathan L. Curry
      Pages 181-191
    6. Molecular Platforms for Melanoma Mutation Analysis

      • Alaa A. Salim, Keyur Pravinchandra Patel
      Pages 193-203
  5. Melanoma Therapeutics

    1. Front Matter

      Pages 205-205
    2. Immunotherapy in Melanoma

      • Van A. Trinh, Yeorim Ahn, Wen-Jen Hwu
      Pages 207-236
    3. Targeted Therapy in Melanoma

      • Isabella C. Glitza, Dae Won Kim, Young Kwang Chae, Kevin B. Kim
      Pages 237-265
    4. Dermatologic Toxicities to Melanoma Targeted Therapies

      • Jonathan L. Curry, Ana M. Ciurea, Priyadharsini Nagarajan, Carlos A. Torres-Cabala
      Pages 267-277
  6. Erratum

    • Carlos A. Torres-Cabala, Jonathan L. Curry
    Pages E1-E1
  7. Back Matter

    Pages 279-288

About this book

This book discusses the molecular, biological, pathological, and clinical aspects of melanoma, with special emphasis in the new concepts of melanoma genetics. A multidisciplinary group of experts in Genetics, Dermatology, Pathology, and Melanoma Medical Oncology contribute state-of-the-art knowledge in melanoma research and clinical management, not only exposing the current status of knowledge of the topics but also providing their personal experiences and ideas about the future and potential practical application of the genetic aspects of melanoma. During the last few years we have witnessed an impressive amount of discoveries in the field of melanoma genetics which have changed our approach in understanding the pathogenesis and treatment of this lethal disease. Genetics of Melanoma is a practical approach to melanoma genetic mechanisms and their application in the diagnosis and treatment of this malignancy. It is an essential source of updated information and a powerful tool for clinicians, pathologists, and basic scientists who wish to understand, apply, and investigate the multiple new aspects of melanoma genetics.

Editors and Affiliations

  • Chief of Dermatopathology Section, Associate Professor of Pathology and Der, Houston, USA

    Carlos A. Torres-Cabala

  • The University of Texas MD Anderson Canc, Associate Professor of Pathology and Der, Houston, USA

    Jonathan L. Curry

About the editors

Carlos A. Torres-Cabala, MD, Associate Professor of Pathology and Dermatology, Chief of Dermatopathology Section, The University of Texas MD Anderson Cancer Center, Houston, TX
Jonathan L. Curry, MD, Associate Professor of Pathology and Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX

Bibliographic Information

  • Book Title: Genetics of Melanoma

  • Editors: Carlos A. Torres-Cabala, Jonathan L. Curry

  • Series Title: Cancer Genetics

  • DOI: https://doi.org/10.1007/978-1-4939-3554-3

  • Publisher: Springer New York, NY

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Science+Business Media New York 2016

  • Hardcover ISBN: 978-1-4939-3552-9Published: 12 May 2016

  • Softcover ISBN: 978-1-4939-8076-5Published: 26 May 2018

  • eBook ISBN: 978-1-4939-3554-3Published: 11 May 2016

  • Series ISSN: 2626-1456

  • Series E-ISSN: 2626-1464

  • Edition Number: 1

  • Number of Pages: XV, 288

  • Number of Illustrations: 1 b/w illustrations, 53 illustrations in colour

  • Topics: Human Genetics, Cancer Research, Molecular Medicine

Buy it now

Buying options

eBook USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access