Growth Factors and the Ovary

1. Front Matter

   Pages i-xiii

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2. Ontogeny of the Ovary

   1. Front Matter

      Pages 1-1

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   2. Mesenchymal-Epithelial Interactions in the Growth and Development of the Urogenital Tract

      • G. R. Cunha

      Pages 3-13

   3. Overview of Embryological and Fetal Development of the Ovary and Testis

      • Luciano Zamboni

      Pages 15-22

   4. Role of Second Messengers in Early Differentiation of Gonads and Sex Ducts

      • Anne Grete Byskov, Hanne Tinggaard, Claus Yding Andersen

      Pages 23-32

   5. Ovarian Tumors, Stem Cells and Ontogeny: Imminentes Cognitiones

      • Waldemar A. Schmidt

      Pages 33-58

3. Keynote Speakers

   1. Front Matter

      Pages 59-59

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   2. Growth Factors, Proto-Oncogenes and the Control of Cell Proliferation: Lessons from the Fibroblast

      • Judith Campisi

      Pages 61-73

   3. Molecular Characterization of Fibroblast Growth Factor and Possible Role in Early and Late Embryonic Development

      • Denis Gospodarowicz

      Pages 75-92

4. Growth Factors and the Ovary

   1. Front Matter

      Pages 93-93

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   2. Rodent Studies on the Potential Relevance of Insulin-Like Growth Factor (IGF-I) to Ovarian Physiology

      • Eli Y. Adashi, Carol Resnick, Eleuterio R. Hernandez, Marjorie E. Svoboda, E. Hoyt, David R. Clemmons et al.

      Pages 95-105

   3. Insulin-Like Growth Factors (IGFs) as Autocrine/Paracrine Regulators in the Porcine Ovarian Follicle

      • J. M. Hammond, J. S. Mondschein, S. F. Canning

      Pages 107-120

   4. Regulatory Actions of the Insulin-Like Growth Factor, IGF-I (Somatomedin-C), on Sterol Metabolism by Ovarian Cells

      • Johannes D. Veldhuis

      Pages 121-130

   5. Growth Factor-Gonadotropin Interactions in Ovarian Cells

      • David W. Schomberg

      Pages 131-139

   6. Transforming Growth Factor Production and Action in the Ovarian Follicle: Theca Cell-Granulosa Cell Interactions

      • Michael K. Skinner

      Pages 141-150

   7. Fibroblast Growth Factors as Local Mediators of Gonadal Function

      • Andrew Baird, Naoya Emoto, Shunichi Shimasaki, Ana Maria Gonzalez, Bart Fauser, Aaron J. W. Hsueh

      Pages 151-160

5. Poster Presentation Manuscripts

   1. Front Matter

      Pages 161-161

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   2. Analysis of Binding Sites for IGF-I on Membranes from Granulosa Cells of Small, Medium, and Large Porcine Follicles

      • Vincent W. Hylka, Brigitte Caubo, Sharon A. Tonetta

      Pages 163-168

   3. Binding Sites for IGF-I Identified on Theca Cells from Large Porcine Follicles

      • Brigitte Caubo, Sharon A. Tonetta

      Pages 169-174

   4. The Role of Insulin-Like Growth Factors in Granulosa Cell Steroidogenesis: Studies with a Neutralizing Antibody to IGF-I

      • J. S. Mondschein, S. F. Canning, J. M. Hammond

      Pages 175-180

The First Ovarian Workshop was held in June 1976; its goal was to achieve a collective understanding of current thought on ovarian follicular development and function, and to generate clear definitions of the most important areas to be explored in the future. The Ovarian Workshops quickly became a major biennial event for the community of reproduc­ tive biologists and their students studying ovarian function. As a young graduate student, I gave my first scientific presentation at the First Ovarian Workshop and I have attended all but one of the subsequent meetings. The Workshops provided a unique forum for the sharing ofideas with colleagues studying closely related problems. I was therefore especially pleased to have been asked to organize the Seventh Ovarian Workshop and to be given an opportunity to help perpetuate these important meetings. The Seventh Ovarian Workshop was held on the campus of the University of Puget Sound in Tacoma, Washington on July 31 and August 1, 1988. Serono Symposia USA generously financed and coordinated the meeting. I would like to express my particular thanks to Dr. L. Lisa Kern and Dr. James Posillico for their invaluable help prior to, during, and after the meeting. I would also like to thank Mary Benson and her staff at the University of Puget Sound who made us feel at home in every way.

• assessment
• cell
• chemistry
• growth
• neoplasm
• physiology

• University of Maryland, Baltimore, USA

  Anne N. Hirshfield

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