Overview
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 2842)
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Keywords
- TALE
- CRISPR
- Zinc Fingers
- Chromatin Immunoprecipitation
- scFv–TET1 catalytic domain fusions
About this book
This second volume details new and updated methods covering applications of epigenome editing. Chapters guide readers through general and topical reviews, DNA-binding devices, optimization of the effector domains, readout of epigenome marks, and approaches for delivery at the cellular and organismal level. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.
Authoritative and cutting-edge, Epigenome Editing: Methods and Protocols, Second Editon aims to ensure successful results in the further study of this vital field.
Editors and Affiliations
Bibliographic Information
Book Title: Epigenome Editing
Book Subtitle: Methods and Protocols
Editors: Albert Jeltsch, Marianne Rots
Series Title: Methods in Molecular Biology
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2024
Hardcover ISBN: 978-1-0716-4050-0Due: 25 August 2024
Softcover ISBN: 978-1-0716-4053-1Due: 25 August 2024
eBook ISBN: 978-1-0716-4051-7Due: 25 August 2024
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 2
Number of Pages: X, 578
Number of Illustrations: 10 b/w illustrations, 64 illustrations in colour