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Cancer Cytogenetics and Cytogenomics

Methods and Protocols

  • Book
  • Jul 2024

Overview

Editors:
  1. Jing Christine Ye

    1. Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Henry H. Heng

    1. Center for Molecular Medicine and Genetics, Wayne State University, Detroit, USA

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Includes cutting-edge techniques
  • Provides step-by-step detail essential for reproducible results
  • Contains key implementation advice from the experts

Part of the book series: Methods in Molecular Biology (MIMB, volume 2825)

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Keywords

  • Gene mutation
  • Karyotype dynamics
  • Genome Architecture Theory
  • Cancer evolution
  • Gene interaction networks
  • Genome chaos

About this book

This detailed volume explores the frontiers of this new era in cancer cytogenetics and cytogenomics, focusing on establishing a karyotype as an information-based genomic framework, as well as presenting technological platforms for collecting and analyzing data at the genome level. It begins with several conceptual chapters that introduce ideas such as the Genome Architecture Theory, forcefully emphasizing the importance of cytogenomics in the post-genomics era. The book then proceeds with protocols covering both basic and advanced cytogenetic and cytogenomic methods, as well as diverse experiments beyond traditional cytogenetic platforms, and bioinformatics techniques and resources. Written for the highly successful Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step and readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

 

Authoritative and up-to-date, Cancer Cytogenetics and Cytogenomics: Methods and Protocols serves as an ideal guide to the unique power of this area of research in spatial biology and system-integrated genomics.

Editors and Affiliations

  • Department of Lymphoma/Myeloma, UT MD Anderson Cancer Center, Houston, USA

    Jing Christine Ye

  • Center for Molecular Medicine and Genetics, Wayne State University, Detroit, USA

    Henry H. Heng

Bibliographic Information

  • Book Title: Cancer Cytogenetics and Cytogenomics

  • Book Subtitle: Methods and Protocols

  • Editors: Jing Christine Ye, Henry H. Heng

  • Series Title: Methods in Molecular Biology

  • Publisher: Humana New York, NY

  • eBook Packages: Springer Protocols

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2024

  • Hardcover ISBN: 978-1-0716-3945-0Due: 29 July 2024

  • Softcover ISBN: 978-1-0716-3948-1Due: 29 July 2024

  • eBook ISBN: 978-1-0716-3946-7Due: 29 July 2024

  • Series ISSN: 1064-3745

  • Series E-ISSN: 1940-6029

  • Edition Number: 1

  • Number of Pages: X, 397

  • Number of Illustrations: 16 b/w illustrations, 63 illustrations in colour

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