Overview
- Discusses protocols for peptide synthesis and their biophysical characterizations
- Reviews the applications of Molecular Dynamics Simulation in structure prediction of peptides
- Shows methods for peptide characterization for the potential applications in drug delivery, protein aggregation studies
Part of the book series: Springer Protocols Handbooks (SPH)
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Table of contents (20 protocols)
Keywords
About this book
This protocol book presents reproducible and step-by-step procedures for the peptide synthesis, their characterization and applications. The volume includes an introductory section on in silico modelling of new peptide molecules, Molecular Dynamics Simulations, Docking, Electrostatic fingerprinting of peptides, and other modelling tools for peptide designing and optimization. Further, it covers protocols for the solid phase peptide synthesis, chromatographic and mass spectrometric characterization of peptides. Importantly, it covers methods for biophysical characterizations of peptides for their potential applications as drug delivery vehicles, peptide nano-assembly, bionanocatalysis, protein aggregation diseases, and peptide-based anti-bacterial.
​Editors and Affiliations
About the editor
Dr. Vibin Ramakrishnan is a Professor of Biosciences and Bioengineering at IIT Guwahati. He did his Master’s in Applied Chemistry from Cochin University of Science and Technology and Ph.D. from School of Biosciences and Bioengineering, IIT Bombay. He worked as a Postdoctoral Research Associate at Rennsselaer Polytechnic Institute, New York and a Faculty scientist at IBAB Bangalore, before joining Department of Biosciences & Bioengineering at IITG. He has published more than 50 research articles in reputed international journals and filed 10 patents, including an international patent to his credit. He is also the principal scientific advisor of two biotech companies.
The Department of Biotechnology, Govt. of India has awarded Dr. Vibin, the Innovative Young Biotechnologist Award (IYBA) in the year 2007-08 to recognize his contributions and for innovative approach in biotechnology research. Dr. Vibin is an editorial board member of Scientific Reports. He has more than15 years of teaching experience in Biophysics, Computational Biology, Bio-techniques, Analytical Biotechnology, and Proteomics. He is a member of many international scientific societies such as American Chemical Society, Biophysical Society, and Protein Society.
​Bibliographic Information
Book Title: Biophysical Characterization of Functional Peptides
Editors: Vibin Ramakrishnan
Series Title: Springer Protocols Handbooks
DOI: https://doi.org/10.1007/978-1-0716-3405-9
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Nature 2023
Hardcover ISBN: 978-1-0716-3404-2Published: 03 August 2023
Softcover ISBN: 978-1-0716-3407-3Due: 03 September 2023
eBook ISBN: 978-1-0716-3405-9Published: 02 August 2023
Series ISSN: 1949-2448
Series E-ISSN: 1949-2456
Edition Number: 1
Number of Pages: XIV, 139
Number of Illustrations: 21 b/w illustrations, 25 illustrations in colour
Topics: Protein Science, Biological and Medical Physics, Biophysics, Biotechnology