Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 2583)
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Table of contents (14 protocols)
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Front Matter
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Cellular Analyses of Neural Progenitors
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Front Matter
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Analyses of Neural Progenitors In Situ
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Front Matter
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RNA-seq Analysis with Single-Cell Resolution (scRNA-seq)
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Front Matter
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Behavioral Phenotyping in Neonatal Mice
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Front Matter
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About this book
This volume discusses the latest imaging and molecular techniques for studying microcephaly through neural progenitor proliferation, survival, and gene expression. All of the methods covered in this book use the mouse as a model system, and include cellular, metabolic, transcriptomic studies of neural progenitors, MR imaging studies of brain growth in 3-dimensions and developmentally-adapted studies of behavior in neonatal mice. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.
Cutting-edge and comprehensive, Microcephaly: Methods and Protocols is a valuable resource for all researchers who want to expand their knowledge and understanding of this important and developing field.
Editors and Affiliations
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Department of Pediatrics, Children’s Center for Neuroscience Research, Emory University School of Medicine, Atlanta, USA
Timothy Gershon
Bibliographic Information
Book Title: Microcephaly
Book Subtitle: Methods and Protocols
Editors: Timothy Gershon
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-0716-2752-5
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2023
Hardcover ISBN: 978-1-0716-2751-8Published: 24 November 2022
Softcover ISBN: 978-1-0716-2754-9Published: 24 November 2023
eBook ISBN: 978-1-0716-2752-5Published: 23 November 2022
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: X, 176
Number of Illustrations: 12 b/w illustrations, 24 illustrations in colour
Topics: Neurosciences