Editors:
- Includes cutting-edge methods and protocols
- Provides step-by-step detail essential for reproducible results
- Contains key notes and implementation advice from the experts
Part of the book series: Methods in Molecular Biology (MIMB, volume 2552)
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Table of contents (27 protocols)
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Front Matter
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Information of Antibody Sequences and Structures
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Front Matter
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Modeling Antibody Structures and Dynamics
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Front Matter
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Prediction and Optimization of Biological and Biophysical Properties of Antibodies
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Front Matter
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Prediction of Antibody-Antigen Interactions
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Front Matter
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About this book
This volume details state-of-the- art methods on computer-aided antibody design. Chapters guide readers through information on antibody sequences and structures, modeling antibody structures and dynamics, prediction and optimization of biological and biophysical properties of antibodies, prediction of antibody-antigen interactions, and computer-aided antibody affinity maturation and beyond. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.
Authoritative and cutting-edge, Computer-Aided Antibody Design aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.
Chapter 2 is available open access under a Creative Commons Attribution 4.0 InternationalLicense via link.springer.com.
Editors and Affiliations
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School of Engineering, The University of Tokyo, Tokyo, Japan
Kouhei Tsumoto, Daisuke Kuroda
Bibliographic Information
Book Title: Computer-Aided Antibody Design
Editors: Kouhei Tsumoto, Daisuke Kuroda
Series Title: Methods in Molecular Biology
DOI: https://doi.org/10.1007/978-1-0716-2609-2
Publisher: Humana New York, NY
eBook Packages: Springer Protocols
Copyright Information: Springer Science+Business Media, LLC, part of Springer Nature 2023
Hardcover ISBN: 978-1-0716-2608-5Published: 09 November 2022
Softcover ISBN: 978-1-0716-2611-5Published: 10 November 2023
eBook ISBN: 978-1-0716-2609-2Published: 08 November 2022
Series ISSN: 1064-3745
Series E-ISSN: 1940-6029
Edition Number: 1
Number of Pages: XIV, 491
Number of Illustrations: 21 b/w illustrations, 118 illustrations in colour
Topics: Antibodies, Bioinformatics, Pharmaceutical Sciences/Technology