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Table of contents (10 chapters)
Keywords
About this book
Modulating Gene Expression by Antisense Oligonucleotides to Understand Neural Functioning addresses the origins of that controversy and determines whether the nervous system is a privileged site for antisense oligonucleotide action and not subject to the same vagaries and pitfalls as non-neuronal systems.
Modulating Gene Expression by Antisense Oligonucleotides to Understand Neural Functioning contains chapters by experts in the field that focus on the use of this technique in a variety of behavioral systems, as well as rapid and nonspecific effects and the uptake and metabolism of antisense oligonucleotides by the nervous system.
Modulating Gene Expression by Antisense Oligonucleotides to Understand Neural Functioning features:
- experts in the field reporting on the use of antisense oligonucleotide technology in a variety of behavioral systems, including pain control, circadian rhythms, ingestion and control of water balance, and reproductive behaviors;
- the novel use of plasmids to express antisense RNA in the nervous system;
- the biodistribution and metabolism of antisense oligonucleotides in the nervous system;
- rapid and unusual effects; and
- non-specific effects.
Editors and Affiliations
Bibliographic Information
Book Title: Modulating Gene Expression by Antisense Oligonucleotides to Understand Neural Functioning
Editors: Margaret M. McCarthy
Series Title: Perspectives in Antisense Science
DOI: https://doi.org/10.1007/978-1-4615-4933-8
Publisher: Springer New York, NY
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eBook Packages: Springer Book Archive
Copyright Information: Springer Science+Business Media New York 1998
Hardcover ISBN: 978-0-7923-8242-3Published: 31 October 1998
Softcover ISBN: 978-1-4613-7238-7Published: 12 October 2012
eBook ISBN: 978-1-4615-4933-8Published: 06 December 2012
Series ISSN: 1566-0389
Edition Number: 1
Number of Pages: XI, 172
Topics: Neurosciences, Neurology, Biochemistry, general