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Ion Channels

Volume 3

  • Book
  • © 1992

Overview

Editors:
  1. Toshio Narahashi

    1. Northwestern University Medical School, Chicago, USA

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Part of the book series: Ion Channels (IC)

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Table of contents (10 chapters)

  1. Front Matter

    Pages i-xv
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  2. Developmental Regulation of Potassium Channels and the Impact on Neuronal Differentiation

    • A. B. Ribera, N. C. Spitzer
    Pages 1-38

  3. Voltage-Gated Calcium Channels in Adult Hippocampal Neurons

    • Daniel Johnston, Ronald Fisher, Richard Gray
    Pages 39-62

  4. Amino ACID Receptor-Mediated Synaptic Currents in the CA1 Region of the Hippocampus

    • Andy D. Randall, Graham L. Collingridge
    Pages 63-81

  5. Intracellular Regulation of GABAA-Receptor Function

    • Armin Stelzer
    Pages 83-136

  6. AXON Terminal Hyperexcitability Seen in Epileptogenesis In Vitro

    • Steven F. Stasheff, Wilkie A. Wilson
    Pages 137-157

  7. Neural Correlates of Memory Storage

    • C. Collin, D. L. Alkon
    Pages 159-175

  8. Functional Regulation of Nicotinic Acetylcholine Receptor Channels in Muscle

    • C. G. Caratsch, F. Grassi, F. Eusebi
    Pages 177-206

  9. Rapid Activation and Desensitization of Transmitter-Liganded Receptor Channels by Pulses of Agonists

    • J. Dudel, C. Franke, H. Hatt
    Pages 207-260

  10. Neurogenetic Studies of Ion Channels in Drosophila

    • Chun-Fang Wu, Barry Ganetzky
    Pages 261-314

  11. Kinetic Properties and Regulation of GABAA Receptor Channels

    • Robert L. Macdonald, Roy E. Twyman
    Pages 315-343

  12. Back Matter

    Pages 345-350
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Keywords

About this book

In the past few years, the scientific community has witnessed significant progress in the study of ion channels. Technological advancement in biophysics, molecular biology, and immunology has been greatly ac­ celerated, making it possible to conduct experiments which were deemed very difficult if not impossible in the past. For example, patch-clamp techniques can now be used to measure ionic currents generated by almost every type of cell, thereby allowing us to analyze whole-cell and single­ channel events. It is now possible to incorporate purified ion channel components into lipid bilayers to reconstitute an "excitable membrane." Gene cloning and monoclonal antibody techniques provide us with new approaches to the study of the molecular structure of ion channels. A variety of chemicals have now been found to interact with ion channels. One of the classical examples is represented by tetrodotoxin, a puffer fish poison, which was shown in the early 1960s to block the voltage-activated sodium channel in a highly specific and potent manner.

Editors and Affiliations

  • Northwestern University Medical School, Chicago, USA

    Toshio Narahashi

Bibliographic Information

  • Book Title: Ion Channels

  • Book Subtitle: Volume 3

  • Editors: Toshio Narahashi

  • Series Title: Ion Channels

  • DOI: https://doi.org/10.1007/978-1-4615-3328-3

  • Publisher: Springer New York, NY

  • eBook Packages: Springer Book Archive

  • Copyright Information: Springer Science+Business Media New York 1992

  • Hardcover ISBN: 978-0-306-44166-0Published: 31 October 1992

  • Softcover ISBN: 978-1-4613-6466-5Published: 05 May 2013

  • eBook ISBN: 978-1-4615-3328-3Published: 06 December 2012

  • Edition Number: 1

  • Number of Pages: XV, 352

  • Topics: Animal Physiology, Biological and Medical Physics, Biophysics, Neurosciences

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