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Mechanisms and Emerging Therapies in Tremor Disorders

  • Book
  • © 2023
  • Latest edition

Overview

Editors:
  1. Giuliana Grimaldi

    1. U.O.C. Unità Spinale, Villa delle Ginestre, ASP Palermo, Palermo, Italy

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    You can also search for this editor in PubMed   Google Scholar

  2. Mario Manto

    1. Service des Neurosciences, Université de Mons, Mons, Belgium

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    You can also search for this editor in PubMed   Google Scholar

  • Details the various forms of tremor encountered in humans
  • Presents recent advances in methodologies and techniques of assessment
  • Covers the latest guidelines of the Tremor Task Force of the International Parkinson and Movement Disorder Society

Part of the book series: Contemporary Clinical Neuroscience (CCNE)

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Table of contents (23 chapters)

  1. Front Matter

    Pages i-x
    Download chapter PDF

  2. Definition of Tremor

    • Giuliana Grimaldi, Mario Manto
    Pages 1-11

  3. Membrane Mechanisms of Tremor

    • Hemani Ticku, Neel Fotedar, Aasef G. Shaikh
    Pages 13-41

  4. Advances in the Genetics of Human Tremor

    • Fabio Coppedè
    Pages 43-74

  5. Two Origins of Tremors Related to the Guillain-Mollaret Triangle: The Forward Model-Related Tremor and the Inferior Olive Oscillation-Related Tremor

    • Shinji Kakei, Mario Manto, Hirokazu Tanaka, Hiroshi Mitoma
    Pages 75-98

  6. Physiologic Tremor

    • Rodger J. Elble
    Pages 99-110

  7. Rest Tremor

    • Giuliana Grimaldi, Mario Manto
    Pages 111-124

  8. Postural Tremors

    • Jean-François Daneault, Christian Duval
    Pages 125-150

  9. Isometric Tremor

    • Jan Raethjen, Dennis A. Nowak
    Pages 151-167

  10. Essential Tremor and Other Forms of Kinetic Tremor

    • Elan D. Louis
    Pages 169-202

  11. Dystonic Tremor

    • Stefania Lalli, Alberto Albanese
    Pages 203-217

  12. Cerebellar Lesions and Tremor

    • Andrea Kovács, Anita Kamondi
    Pages 219-245

  13. Orthostatic Tremor

    • Julián Benito-León, Ritwik Ghosh, Souvik Dubey, Elan D. Louis
    Pages 247-269

  14. Posttraumatic Tremor and Other Posttraumatic Movement Disorders

    • Jose Fidel Baizabal-Carvallo, Joseph Jankovic
    Pages 271-301

  15. Tremor in Childhood

    • Padraic J. Grattan-Smith, Russell C. Dale
    Pages 303-321

  16. Metabolic Causes of Tremor

    • Diksha Mohanty, Peter Hedera
    Pages 323-343

  17. Tremor: The Clinical Approach to Reach the Diagnosis

    • Julian Agin-Liebes, Sheng-Han Kuo
    Pages 345-367

  18. Signal Processing

    • James McNames
    Pages 369-391

  19. Diffusion Imaging in Tremor

    • Johannes C. Klein
    Pages 393-406

  20. The Role of the Noradrenergic System in Tremor Pathogenesis

    • Rick C. Helmich, Anouk van der Heide, Michiel F. Dirkx
    Pages 407-426
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Keywords

About this book

Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness, and damping are all factors that influence the features of tremor. This completely updated new edition discusses the pathophysiology of tremor, including membrane mechanisms and rodent models, the advances in genetics, and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment and provides practical information for daily management. This new edition is informed by the guidelines of the Tremor Task Force of the International Parkinson and Movement Disorders Society.  New chapters include Classification of Tremors, Medically Induced Tremors, Resting State fMRI, and Gabaergic Pathways. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced.

Editors and Affiliations

  • U.O.C. Unità Spinale, Villa delle Ginestre, ASP Palermo, Palermo, Italy

    Giuliana Grimaldi

  • Service des Neurosciences, Université de Mons, Mons, Belgium

    Mario Manto

About the editors

Giuliana Grimaldi, MD, PhD, is a neurologist.  She is affiliated with Unità Spinale, ASP Palermo, Italy. She is a member of the Society for Cerebellar Research (SRC).



Mario Manto, MD, PhD is a neurologist. He is researcher at the FNRS-Belgium, Head of the Department of Neurology, CHU-Charleroi, and Professor of Neuroanatomy at U Mons.  He is the founding and current editor of the international journal The Cerebellum (Springer). He is the President of the Medical Board of Euro-Ataxia. He has founded the Society for Research on the Cerebellum.  He is editor of the Contemporary Clinical Neuroscience series (Springer).

Bibliographic Information

  • Book Title: Mechanisms and Emerging Therapies in Tremor Disorders

  • Editors: Giuliana Grimaldi, Mario Manto

  • Series Title: Contemporary Clinical Neuroscience

  • DOI: https://doi.org/10.1007/978-3-031-26128-2

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2023

  • Hardcover ISBN: 978-3-031-26127-5Published: 21 October 2023

  • Softcover ISBN: 978-3-031-26130-5Due: 21 November 2023

  • eBook ISBN: 978-3-031-26128-2Published: 20 October 2023

  • Series ISSN: 2627-535X

  • Series E-ISSN: 2627-5341

  • Edition Number: 2

  • Number of Pages: X, 558

  • Number of Illustrations: 27 b/w illustrations, 59 illustrations in colour

  • Topics: Biomedicine, general, Neurology, Neurosciences, Neurosciences

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