Overview
- Covers basic model studies of novel biomarkers and treatment targets of the microenvironment
- Explores a variety of different classes of biomarkers in human tumors
- Features new chapters covering the use of artificial intelligence and imaging mass cytometry
- Contains mechanisitic data and information on the latest studies of human tumor tissue
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Table of contents (34 chapters)
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Front Matter
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Basic Studies: Tumor Mechanisms and Tissue Biomarkers
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Front Matter
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Keywords
About this book
This book reviews different aspects of the cancer microenvironment, and its regulation and importance for tumor progression. Methodological advancements and practical applications, in terms of how biomarkers are studied and increasingly included in clinical trials and therapy protocols, are described and discussed.
Biomarkers of the Tumor Microenvironment is an educational resource for students and members of the cancer research community as a whole, especially for those using morphology analysis techniques and models focusing on the cross-talk between different cell types in tumors. The textbook provides a comprehensive overview of the microenvironment in various contexts from the perspectives of experienced and accomplished cancer researchers and clinicians.
Editors and Affiliations
About the editors
Lars A. Akslen is a professor of medicine (tumor pathology) at the University of Bergen (Bergen, Norway), a senior consultant in surgical pathology at Haukeland University Hospital, and a director of the Centre for Cancer Biomarkers CCBIO, a Norwegian Center of Excellence. Dr. Akslen is working on biomarkers of the tumor microenvironment and how these can be defined and reported on tissue specimens from human cancers, in particular breast tumors. Angiogenesis and immune responses represent the main areas of interest.
Randolph S. Watnick is a trained molecular biologist and is currently a research associate at the Vascular Biology Program, Boston Children´s Hospital (Boston, USA), and an assistant professor at the Department of Surgery, Harvard Medical School. After receiving his Ph.D., Dr. Watnick continued his training as a post-doctoral fellow in the laboratory of Dr. Robert Weinberg at the Whitehead Institute for Biomedical Research. Dr.Watnick is now working on mechanisms of how the tumor microenvironment promotes cancer progression, with particular focus on roles of the immune system and vascular structures.
Bibliographic Information
Book Title: Biomarkers of the Tumor Microenvironment
Editors: Lars A. Akslen, Randolph S. Watnick
DOI: https://doi.org/10.1007/978-3-030-98950-7
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2022
Hardcover ISBN: 978-3-030-98949-1Published: 14 July 2022
Softcover ISBN: 978-3-030-98952-1Published: 14 July 2023
eBook ISBN: 978-3-030-98950-7Published: 12 July 2022
Edition Number: 2
Number of Pages: XVII, 593
Number of Illustrations: 1 b/w illustrations, 111 illustrations in colour
Topics: Pathology, Oncology, Medicine/Public Health, general