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Biomedical Sciences - Pharmacology & Toxicology | Journal of Natural Medicines

Journal of Natural Medicines

Journal of Natural Medicines

Chief Editor: Masami Ishibashi

ISSN: 1340-3443 (print version)
ISSN: 1861-0293 (electronic version)

Journal no. 11418

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Instructions for Authors

Editorial policy 

Before preparation of your manuscript, read the 'Instructions for Authors' carefully. We will not accept manuscripts that do not comply with these instructions.
The Journal of Natural Medicines invites papers that make a significant contribution to the knowledge and understanding of naturally occurring medicines and their related foods and cosmetics, including identification and structure elucidation of natural products, biosynthesis, biotechnology, and pharmacology of herbs, natural products, and Kampo formulas. Papers are also published concerning chemical and botanical identification of herbs or their products where such information contributes to the overall safety of plant-based medicines currently and/or formerly in use. Submission of a paper implies that it has been approved by all the named authors, that it has not been published before, and that it is not under consideration for publication elsewhere.
Acceptance of papers will be decided by the Editorial Board after examination by at least two referees. Manuscripts that require revision and/or correction and/or condensation will be returned to the authors with comments specifying alterations from the referees and/or the Editorial Board.
The following types of papers may be submitted. (i) Original Papers: Original Papers are the usual form of publication of this journal describing original experimental results. (ii) Notes (up to 4 printed pages): Notes are brief articles reporting new facts and/or valuable data. (iii) Rapid Communications (up to 3 printed pages): These are short preliminary reports of novel and significant findings that merit urgent publication. Full details of the Rapid Communication may be published later as a comprehensive original paper, in this or another journal. An explanatory statement is required for urgent publication. (iv) Reviews (up to 12 printed pages): Reviews cover recent discoveries or topics of current interest. (v) Mini-Reviews (up to 6 printed pages): These provide a short overview of a particular subject. In the case of a non-invited Review or Mini-Review, a short summary describing the outline should be sent to the Chief Editor for approval before submitting a manuscript. (vi) Natural Resource Letters (up to 6 printed pages): Natural Resource Letters are reports on biological screening data, field observations, market surveys, quality evaluation or quantitative methods of crude drugs, etc., which may contribute to the scientific knowledge of the readers.
  • Documentation of experimental biological materials.
    Use the correct scientific name and indicate who identified the biological materials. The herbarium deposit site and voucher number should be recorded. Authors who purchase herbal materials from companies must make provision for their deposit in a herbarium.
  • Pharmacological investigations of extracts require detailed extract characterization.
    This includes botanical characterization of plant material(s), solvent(s), duration and temperature of extraction, plus other method(s) used for preparation(s). A chromatographic (e.g., HPLC profile recorded at different wavelengths) or chemical characterization (quantities of typical constituents) must be presented. The investigation must clearly indicate a dose/activity dependence in comparison with a reference compound (positive control) together with the appropriate statistics. Authors must mention it in the main text if there was no appropriate reference compound available.
  • Criteria of Authorship
    Authorship should be based on the International Committee of Medical Journal Editors (ICJME) recommendations concerning authorship (http://www.icmje.org/recommendations/browse/roles-and-responsibilities/definingthe-role-of-authors-and-contributors.html). All authors are required to meet the following 4 criteria:
    ・Substantial contribution to the conception or design of the work; or the acquisition, analysis, or interpretation of data for the work; AND
    ・ Drafting the work or revising it critically for important intellectual content; AND
    ・ Final approval of the version to be published; AND
    ・ Agreement to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.
  • Other Rules of the Editorial Committee
    The following manuscripts are not currently accepted as Original Papers.
    ・Preliminary screening tests of extracts, such as
    a) Antimicrobial and cytotoxic screening tests of extracts, including essential oils.
    b) Antioxidant or radical scavenging in vitro tests.
    ・Pharmacological studies of extracts and their fractions without an HPLC profile.
    ・Reports of preliminary quantitative analyses using common HPLC methods.
    ・Clinical studies and studies of safety and toxicity in experimental animals. The editorial committee recommends submitting such manuscripts to another journal.
  • Chief Editor: Masami Ishibashi
    E-mail: mish@chiba-u.jp

Page Charges 

The following charges are to be paid within one month after publication of a paper in the printed issue.
(i) Handling charges: JPY 4,000 per printed page.
(ii) Charges for excess pages in Notes, Rapid Communications and Natural Resource Letters: JPY 8,000 per printed page in addition to the handling charges.

Online Submission 

Authors should submit their manuscripts online. Electronic submission substantially reduces the editorial processing and reviewing times and shortens overall publication times. Please log directly onto the link below and upload all your manuscript files following the instructions given on the screen.

Legal requirements 

The author(s) guarantee(s) that the manuscript will not be published elsewhere in any language without the consent of The Japanese Society of Pharmacognosy and Springer, that the rights of third parties will not be violated, and that the publisher will not be held legally responsible should there be any claims for compensation.
Authors wishing to include figures or text passages that have already been published elsewhere are required to obtain permission from the copyright owner(s) and to include evidence that such permission has been granted when submitting their papers. Any material received without such evidence will be assumed to originate from the authors.

Manuscript preparation 

Manuscripts must be written in English using Times font and typed in double-line spacing with 3-cm margins; pages should be numbered. Authors whose first language is not English are urged to have their manuscript read by a colleague who is a native English speaker and is familiar with their field of work before submitting the paper.
Manuscripts with extensive English language deficiencies will be returned to the author without the full reviewing process.
The manuscript should be arranged as follows:
  • Title page (including an article title, name(s) of author(s), affiliation(s) and address(es) of the author(s), e-mail address and telephone number(s) of the corresponding author, and the 16 digit ORCID of the aurhot(s) if available.)
  • Abstract (200-250 words)
  • Four to six keywords
  • Text of the paper: Introduction; main text (divided into sections, if appropriate); Acknowledgments; References; tables; figure legends
  • Abbreviations. Abbreviations must be spelled out in full at their initial appearance in the abstract and main text, followed by the abbreviation in parentheses. Thereafter, the abbreviation may be employed.
    However, the following need not be defined : AIDS (acquired immunodeficiency syndrome), ATP (adenosine 5'-triphosphate), cAMP (adenosine 3',5'-cyclic monophosphate), CD (circular dichroism), cDNA (complementary DNA), CoA (coenzyme A), COSY (correlated spectroscopy), DNA (deoxyribonucleic acid), ED50 (50% effective dose), EI-MS (electron ionization mass spectrometry), FAB-MS (fast atom bombardment mass spectrometry), FAD (flavin adenine dinucleotide), GC-MS (gas chromatography-mass spectrometry), HMBC (heteronuclear multiple bond connectivity), HMQC (heteronuclear multiple quantum coherence), HPLC (high-pressure liquid chromatography, high-performance liquid chromatography), HSQC (heteronuclear single quantum coherence), IC50 (inhibitory concentration, 50%), IR (infrared), LD50 (50% lethal dose), mRNA (messenger RNA), MS (mass spectrum), NMR (nuclear magnetic resonance, as 13C-NMR, 1H-NMR), NOE (nuclear Overhauser effect), NOESY (nuclear Overhauser and exchange spectroscopy), ORD (optical rotatory dispersion), P450 (as in cytochrome P450), RNA (ribonucleic acid), rRNA (ribosomal RNA), TLC (thin-layer chromatography), tRNA (transfer RNA), UV (ultraviolet).
  • Units. The following units should be used: length (m, cm, mm, μm, nm, Å), mass (kg, g, mg, μg, ng, pg, mol, mmol), volume (l, ml, μl), time (s, min, h, d), temperature (°C, K), radiation (Bq, Ci, dpm, Gy, rad), concentration (M, mM, mol/l, mmol/l, mg/ml, μg/ml, %, %(v/v), % (w/v), ppm, ppb).
  • Spectral and elemental analysis data. Please report spectral and elemental analysis data in the following format, 1H-NMR (CDCl3) δ:1.25 (3H, d, J=7.0 Hz), 3.55 (1H, q, J=7.0 Hz), 6.70 (1H, m). 13C-NMR (CDCl3) δ:20.9 (q), 71.5 (d), 169.9 (s). IR (KBr) cm-1: 1720, 1050, 910. UV λmax(H2O) nm (log ε):280 (3.25). MS m/z :332 (M+), 180, 168. HRFAB-MS m/z:332.1258 (Calcd for C18H20O6: 332.1259). [α]D23—74.5° (c 1.0, MeOH). Anal. Calcd for C19H21NO3:C, 73.29; H, 6.80; N, 4.50. Found: C, 73.30; H, 6.88; N, 4.65.
  • Nomenclature. The nomenclature of chemical compounds should be in accordance with the nomenclature rules formulated by IUPAC. Alternatively, naming may conform to the nomenclature in the index of Chemical Abstracts or the Ring Index.
  • X-ray crystal structure analyses. When structure determination by X-ray crystallographic analysis is a central theme of the paper, the data required for registration with the Cambridge Crystallographic Data Base (CCDB) should be attached as supplementary material. Although this does not apply in cases where crystallographic analysis plays only a supplementary role, crystal data (unit cell parameters, space group, Z density) and R-factor should still be noted. Atomic coordinates, bond lengths and angles, thermal parameters, and torsion angles should be presented when they are important for the issues addressed in the paper. When papers have been accepted, the authors are advised to register the data with CCDB.
  • Chemical structures. The graphics for chemical structure should be created with drawing programs such as ChemDraw (ChemBioDraw) and use of the ACS 1996 document settings is preferred.


The list of References should include only works that are cited in the text and that have been published or accepted for publication. Personal communications should be mentioned only in the text. If available, the DOI can be added at the end of the reference in question.
References should be numbered in the order in which they appear in the text and be listed in numerical order. Journal titles should be abbreviated according to Chemical Abstracts. References should be styled as follows, with correct punctuation:
1. Kuroyanagi M, Umehara K, Hayashi T, Hirayama Y (2002) Cell differentiation inducers and antiandrogenic active compounds from zingiberis rhizoma. Nat Med 56:47–50
2. Chen W, Punja Z (2002) Agrobacterium-mediated transformation of American ginseng with a rice chitinase gene. Plant Cell Rep 20:1039–1045 DOI 10.1007/s00299-002-0446-z
3. Tsukaya H, Iokawa Y, Kondo M, Ohba H (2005) Large-scale general collection of wild-plant DNA in Mustang, Nepal. J Plant Res DOI 10.1007/s10265-005-0196-4
4. Capasso F, Gaginella TS, Grandolini G., Izzo AA (2003) Phytotherapy. Springer, Berlin Heidelberg New York
5. Bauer BA (2003) Herbal therapy and the elderly. In: Cherniack P, Cherniack N (eds) Alternative medicine for the elderly. Springer, Berlin Heidelberg New York, pp 111–132

Graphical abstract 

To give the reader a representative idea of the topic discussed in the paper, the authors can submit a graphical abstract figure (chemical structures, charts, graphs, images, or other informative illustrations) with their manuscript. The graphical abstract figure must be original and not previously published, and should be prepared in one of the following file types: .tiff, .eps, .jpg, .bmp, .doc, or .pdf. It should be no wider than 8 cm and no taller than 4 cm when printed at full scale (100%).


  • All tables are to be numbered using Arabic numerals.
  • Tables should always be cited in text in consecutive numerical order.
  • For each table, please supply a table caption (title) explaining the components of the table.
  • Identify any previously published material by giving the original source in the form of a reference at the end of the table caption.
  • Footnotes to tables should be indicated by superscript lower-case letters (or asterisks for significance values and other statistical data) and included beneath the table body.

Artwork and Illustrations Guidelines 

Electronic Figure Submission

  • Supply all figures electronically.
  • Indicate what graphics program was used to create the artwork.
  • For vector graphics, the preferred format is EPS; for halftones, please use TIFF format. MSOffice files are also acceptable.
  • Vector graphics containing fonts must have the fonts embedded in the files.
  • Name your figure files with "Fig" and the figure number, e.g., Fig1.eps.

Line Art

Line BW
  • Definition: Black and white graphic with no shading.
  • Do not use faint lines and/or lettering and check that all lines and lettering within the figures are legible at final size.
  • All lines should be at least 0.1 mm (0.3 pt) wide.
  • Scanned line drawings and line drawings in bitmap format should have a minimum resolution of 1200 dpi.
  • Vector graphics containing fonts must have the fonts embedded in the files.

Halftone Art

Halftone gray color
  • Definition: Photographs, drawings, or paintings with fine shading, etc.
  • If any magnification is used in the photographs, indicate this by using scale bars within the figures themselves.
  • Halftones should have a minimum resolution of 300 dpi.

Combination Art

  • Definition: a combination of halftone and line art, e.g., halftones containing line drawing, extensive lettering, color diagrams, etc.
  • Combination artwork should have a minimum resolution of 600 dpi.

Color Art

  • Color art is free of charge for online publication.
  • If black and white will be shown in the print version, make sure that the main information will still be visible. Many colors are not distinguishable from one another when converted to black and white. A simple way to check this is to make a xerographic copy to see if the necessary distinctions between the different colors are still apparent.
  • If the figures will be printed in black and white, do not refer to color in the captions.
  • Color illustrations should be submitted as RGB (8 bits per channel).

Figure Lettering

  • To add lettering, it is best to use Helvetica or Arial (sans serif fonts).
  • Keep lettering consistently sized throughout your final-sized artwork, usually about 2–3 mm (8–12 pt).
  • Variance of type size within an illustration should be minimal, e.g., do not use 8-pt type on an axis and 20-pt type for the axis label.
  • Avoid effects such as shading, outline letters, etc.
  • Do not include titles or captions within your illustrations.

Figure Numbering

  • All figures are to be numbered using Arabic numerals.
  • Figures should always be cited in text in consecutive numerical order.
  • Figure parts should be denoted by lowercase letters (a, b, c, etc.).
  • If an appendix appears in your article and it contains one or more figures, continue the consecutive numbering of the main text. Do not number the appendix figures,
    "A1, A2, A3, etc." Figures in online appendices (Electronic Supplementary Material) should, however, be numbered separately.

Figure Captions

  • Each figure should have a concise caption describing accurately what the figure depicts. Include the captions in the text file of the manuscript, not in the figure file.
  • Figure captions begin with the term Fig. in bold type, followed by the figure number, also in bold type.
  • No punctuation is to be included after the number, nor is any punctuation to be placed at the end of the caption.
  • Identify all elements found in the figure in the figure caption; and use boxes, circles, etc., as coordinate points in graphs.
  • Identify previously published material by giving the original source in the form of a reference citation at the end of the figure caption.

Figure Placement and Size

  • Figures should be submitted separately from the text, if possible.
  • When preparing your figures, size figures to fit in the column width.
  • For most journals the figures should be 39 mm, 84 mm, 129 mm, or 174 mm wide and not higher than 234 mm.
  • For books and book-sized journals, the figures should be 80 mm or 122 mm wide and not higher than 198 mm.


If you include figures that have already been published elsewhere, you must obtain permission from the copyright owner(s) for both the print and online format. Please be aware that some publishers do not grant electronic rights for free and that Springer will not be able to refund any costs that may have occurred to receive these permissions. In such cases, material from other sources should be used.


In order to give people of all abilities and disabilities access to the content of your figures, please make sure that
  • All figures have descriptive captions (blind users could then use a text-to-speech software or a text-to-Braille hardware)
  • Patterns are used instead of or in addition to colors for conveying information (colorblind users would then be able to distinguish the visual elements)
  • Any figure lettering has a contrast ratio of at least 4.5:1

Ethical Responsibilities of Authors 

This journal is committed to upholding the integrity of the scientific record. As a member of the Committee on Publication Ethics (COPE) the journal will follow the COPE guidelines on how to deal with potential acts of misconduct.
Authors should refrain from misrepresenting research results which could damage the trust in the journal, the professionalism of scientific authorship, and ultimately the entire scientific endeavour. Maintaining integrity of the research and its presentation is helped by following the rules of good scientific practice, which include*:
  • The manuscript should not be submitted to more than one journal for simultaneous consideration.
  • The submitted work should be original and should not have been published elsewhere in any form or language (partially or in full), unless the new work concerns an expansion of previous work. (Please provide transparency on the re-use of material to avoid the concerns about text-recycling (‘self-plagiarism’).
  • A single study should not be split up into several parts to increase the quantity of submissions and submitted to various journals or to one journal over time (i.e. ‘salami-slicing/publishing’).
  • Concurrent or secondary publication is sometimes justifiable, provided certain conditions are met. Examples include: translations or a manuscript that is intended for a different group of readers.
  • Results should be presented clearly, honestly, and without fabrication, falsification or inappropriate data manipulation (including image based manipulation). Authors should adhere to discipline-specific rules for acquiring, selecting and processing data.
  • No data, text, or theories by others are presented as if they were the author’s own (‘plagiarism’). Proper acknowledgements to other works must be given (this includes material that is closely copied (near verbatim), summarized and/or paraphrased), quotation marks (to indicate words taken from another source) are used for verbatim copying of material, and permissions secured for material that is copyrighted.
  • Important note: the journal may use software to screen for plagiarism.
  • Authors should make sure they have permissions for the use of software, questionnaires/(web) surveys and scales in their studies (if appropriate).
  • Authors should avoid untrue statements about an entity (who can be an individual person or a company) or descriptions of their behavior or actions that could potentially be seen as personal attacks or allegations about that person.
  • Research that may be misapplied to pose a threat to public health or national security should be clearly identified in the manuscript (e.g. dual use of research). Examples include creation of harmful consequences of biological agents or toxins, disruption of immunity of vaccines, unusual hazards in the use of chemicals, weaponization of research/technology (amongst others).
  • Authors are strongly advised to ensure the author group, the Corresponding Author, and the order of authors are all correct at submission. Adding and/or deleting authors during the revision stages is generally not permitted, but in some cases may be warranted. Reasons for changes in authorship should be explained in detail. Please note that changes to authorship cannot be made after acceptance of a manuscript.
Upon request authors should be prepared to send relevant documentation or data in order to verify the validity of the results presented. This could be in the form of raw data, samples, records, etc. Sensitive information in the form of confidential or proprietary data is excluded.
*All of the above are guidelines and authors need to make sure to respect third parties rights such as copyright and/or moral rights.
If there is suspicion of misbehavior or alleged fraud the Journal and/or Publisher will carry out an investigation following COPE guidelines. If, after investigation, there are valid concerns, the author(s) concerned will be contacted under their given e-mail address and given an opportunity to address the issue. Depending on the situation, this may result in the Journal’s and/or Publisher’s implementation of the following measures, including, but not limited to:
  • If the manuscript is still under consideration, it may be rejected and returned to the author.
  • If the article has already been published online, depending on the nature and severity of the infraction:
    - an erratum/correction may be placed with the article
    - an expression of concern may be placed with the article
    - or in severe cases retraction of the article may occur. The reason will be given in the published erratum, expression of concern or retraction note. Please note that retraction means that the article is maintained on the platform, watermarked “retracted” and the explanation for the retraction is provided in a note linked to the watermarked article.
  • The author’s institution may be informed
  • A notice of suspected transgression of ethical standards in the peer review system may be included as part of the author’s and article’s bibliographic record.

Fundamental errors

Authors have an obligation to correct mistakes once they discover a significant error or inaccuracy in their published article. The author(s) is/are requested to contact the journal and explain in what sense the error is impacting the article. A decision on how to correct the literature will depend on the nature of the error. This may be a correction or retraction. The retraction note should provide transparency which parts of the article are impacted by the error.

Suggesting / excluding reviewers

Authors are welcome to suggest suitable reviewers and/or request the exclusion of certain individuals when they submit their manuscripts. When suggesting reviewers, authors should make sure they are totally independent and not connected to the work in any way. It is strongly recommended to suggest a mix of reviewers from different countries and different institutions. When suggesting reviewers, the Corresponding Author must provide an institutional email address for each suggested reviewer, or, if this is not possible to include other means of verifying the identity such as a link to a personal homepage, a link to the publication record or a researcher or author ID in the submission letter. Please note that the Journal may not use the suggestions, but suggestions are appreciated and may help facilitate the peer review process.

Disclosure of potential conflicts of interest 

Authors must disclose all relationships or interests that could have direct or potential influence or impart bias on the work. Although an author may not feel there is any conflict, disclosure of relationships and interests provides a more complete and transparent process, leading to an accurate and objective assessment of the work. Awareness of a real or perceived conflicts of interest is a perspective to which the readers are entitled. This is not meant to imply that a financial relationship with an organization that sponsored the research or compensation received for consultancy work is inappropriate. Examples of potential conflicts of interests that are directly or indirectly related to the research may include but are not limited to the following:
  • Research grants from funding agencies (please give the research funder and the grant number)
  • Honoraria for speaking at symposia
  • Financial support for attending symposia
  • Financial support for educational programs
  • Employment or consultation
  • Support from a project sponsor
  • Position on advisory board or board of directors or other type of management relationships
  • Multiple affiliations
  • Financial relationships, for example equity ownership or investment interest
  • Intellectual property rights (e.g. patents, copyrights and royalties from such rights)
  • Holdings of spouse and/or children that may have financial interest in the work
In addition, interests that go beyond financial interests and compensation (non-financial interests) that may be important to readers should be disclosed. These may include but are not limited to personal relationships or competing interests directly or indirectly tied to this research, or professional interests or personal beliefs that may influence your research.
The corresponding author collects the conflict of interest disclosure forms from all authors. In author collaborations where formal agreements for representation allow it, it is sufficient for the corresponding author to sign the disclosure form on behalf of all authors. Examples of forms can be found
The corresponding author will include a summary statement in the text of the manuscript in a separate section before the reference list, that reflects what is recorded in the potential conflict of interest disclosure form(s).
See below examples of disclosures:
Funding: This study was funded by X (grant number X).
Conflict of Interest: Author A has received research grants from Company A. Author B has received a speaker honorarium from Company X and owns stock in Company Y. Author C is a member of committee Z.
If no conflict exists, the authors should state:
Conflict of Interest: The authors declare that they have no conflict of interest.

Ethical Standards 

Manuscripts that reveal a lack of ethical consideration for human subjects or experimental animals will not be accepted for publication. All clinical research using human subjects or materials should be conducted in accordance with the Recommendations from the Declaration of Helsinki. For animal experiments, authors should follow the experimental animal guidelines of their institution as well as the appropriate government guidelines, such as those published by the Japanese Ministry of Education, Culture, Sports, Science and Technology. Authors must also indicate in the manuscript that the experimental procedures were approved by the appropriate committee (e.g., Experimental Animal Research Committee) at their institute or university.

Electronic Supplementary Material 

Springer accepts electronic multimedia files (animations, movies, audio, etc.) and other supplementary files to be published online along with an article or a book chapter. This feature can add dimension to the author's article, as certain information cannot be printed or is more convenient in electronic form.
Before submitting research datasets as electronic supplementary material, authors should read the journal’s Research data policy. We encourage research data to be archived in data repositories wherever possible.


  • Supply all supplementary material in standard file formats.
  • Please include in each file the following information: article title, journal name, author names; affiliation and e-mail address of the corresponding author.
  • To accommodate user downloads, please keep in mind that larger-sized files may require very long download times and that some users may experience other problems during downloading.

Audio, Video, and Animations

  • Aspect ratio: 16:9 or 4:3
  • Maximum file size: 25 GB
  • Minimum video duration: 1 sec
  • Supported file formats: avi, wmv, mp4, mov, m2p, mp2, mpg, mpeg, flv, mxf, mts, m4v, 3gp

Text and Presentations

  • Submit your material in PDF format; .doc or .ppt files are not suitable for long-term viability.
  • A collection of figures may also be combined in a PDF file.


  • Spreadsheets should be submitted as .csv or .xlsx files (MS Excel).

Specialized Formats

  • Specialized format such as .pdb (chemical), .wrl (VRML), .nb (Mathematica notebook), and .tex can also be supplied.

Collecting Multiple Files

  • It is possible to collect multiple files in a .zip or .gz file.


  • If supplying any supplementary material, the text must make specific mention of the material as a citation, similar to that of figures and tables.
  • Refer to the supplementary files as “Online Resource”, e.g., "... as shown in the animation (Online Resource 3)", “... additional data are given in Online Resource 4”.
  • Name the files consecutively, e.g. “ESM_3.mpg”, “ESM_4.pdf”.


  • For each supplementary material, please supply a concise caption describing the content of the file.

Processing of supplementary files

  • Electronic supplementary material will be published as received from the author without any conversion, editing, or reformatting.


In order to give people of all abilities and disabilities access to the content of your supplementary files, please make sure that
  • The manuscript contains a descriptive caption for each supplementary material
  • Video files do not contain anything that flashes more than three times per second (so that users prone to seizures caused by such effects are not put at risk)

Research Data Policy 

The journal encourages authors, where possible and applicable, to deposit data that support the findings of their research in a public repository. Authors and editors who do not have a preferred repository should consult Springer Nature’s list of repositories and research data policy.
General repositories - for all types of research data - such as figshare and Dryad may also be used.
Datasets that are assigned digital object identifiers (DOIs) by a data repository may be cited in the reference list. Data citations should include the minimum information recommended by DataCite: authors, title, publisher (repository name), identifier.
Springer Nature provides a research data policy support service for authors and editors, which can be contacted at researchdata@springernature.com.
This service provides advice on research data policy compliance and on finding research data repositories. It is independent of journal, book and conference proceedings editorial offices and does not advise on specific manuscripts.

After acceptance 

Upon acceptance of your article you will receive a link to the special Author Query Application at Springer’s web page where you can sign the Copyright Transfer Statement online and indicate whether you wish to order OpenChoice, offprints, or printing of figures in color. Once the Author Query Application has been completed, your article will be processed and you will receive the proofs.
  • Copyright transfer. Authors will be asked to transfer copyright of the article to the Japanese Society of Pharmacognosy and Springer Japan (or grant the Publisher exclusive publication and dissemination rights). This will ensure the widest possible protection and dissemination of information under copyright laws.
  • Offprints. Offprints can be ordered by the corresponding author.
  • Color illustrations. Online publication of color illustrations is free of charge. For color in the print version, authors will be expected to make a contribution towards the extra costs.Otherwise the figures will be printed in black and white. Please note that, in such cases, it is authors’ responsibility to prepare figures to be illustrative enough to convey the necessary information even after they are converted into black and white.
  • Proof reading. Proofreading is the responsibility of the author. The purpose of the proof is to check for typesetting or conversion errors and the completeness and accuracy of the text, tables and figures. Substantial changes in content, e.g., new results, corrected values, title, and authorship, as well as replacement of figures, are not allowed without the approval of the responsible editor. In such a case the Editorial Office should be contacted before the proofs are returned to the publisher. After online publication, corrections can be made only in exceptional cases and in the form of an Erratum, which will be hyperlinked to the paper.
  • Online First. Papers will be published online about one week after receipt of the corrected proofs. Papers published online can be cited by their DOI immediately. After release of the printed version, the paper can also be cited by issue and page numbers.

Open Choice 

Open Choice allows you to publish open access in more than 1850 Springer Nature journals, making your research more visible and accessible immediately on publication.
Article processing charges (APCs) vary by journal – view the full list
  • Increased researcher engagement: Open Choice enables access by anyone with an internet connection, immediately on publication.
  • Higher visibility and impact: In Springer hybrid journals, OA articles are accessed 4 times more often on average, and cited 1.7 more times on average*.
  • Easy compliance with funder and institutional mandates: Many funders require open access publishing, and some take compliance into account when assessing future grant applications.
It is easy to find funding to support open access – please see our funding and support pages for more information.
*) Within the first three years of publication. Springer Nature hybrid journal OA impact analysis, 2018.

Copyright and license term – CC BY

Open Choice articles do not require transfer of copyright as the copyright remains with the author. In opting for open access, the author(s) agree to publish the article under the Creative Commons Attribution License.

Date of issue 

The journal will be issued in January, April, July, and October each year.
(Revised on 19 November 2018)

For authors and editors

  • Journal Citation Reports®
    2017 Impact Factor
  • 1.920
  • Aims and Scope

    Aims and Scope


    The Journal of Natural Medicines is an international journal publishing original research in naturally occurring medicines and their related foods and cosmetics. It covers

    chemistry of natural products
    biochemistry of medicinal plants
    pharmacology of natural products and herbs, including Kampo formulas and traditional herbs
    botanical anatomy
    cultivation of medicinal plants.

    The journal accepts Original Papers, Notes, Rapid Communications and Natural Resource Letters. Reviews and Mini-Reviews are generally invited.

    Of the papers published in each volume of the Journal of Natural Medicines, approximately three will be chosen by members of the Selection Committee as the Journal of Natural Medicines Award.

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    Instructions for Authors


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    English Language Editing


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